Subitha, S (2020) A Study on Estimating Prevalence of Spontaneous Bacterial Peritonitis in Asymptomatic Outpatients with Cirrhotic Ascites undergoing Therapeutic Tapping. Masters thesis, Coimbatore Medical College, Coimbatore.
|
Text
200100720subitha.pdf Download (3MB) | Preview |
Abstract
INTRODUCTION: Spontaneous bacterial peritonitis (SBP) is most common, potentially lethal and characteristic infectious complication of cirrhosis. SBP is defined as the presence of infection in ascetic fluid in absence of any distinguishable secondary cause of peritonitis. The profile of SBP may differ with different ethnic groups, geographic factors, social factors and etiological factors. Although there is evidence of SBP, from both the developed and developing nations, there has not been any study conducted in India to find out the occurrence of SBP, especially in southern part of India and in a tier II city like Coimbatore. Hence, we intended to conduct this to assess the frequency of Spontaneous Bacterial Peritonitis in asymptomatic outpatients with cirrhotic ascites, through the analysis of ascetic fluid. This further aimed to study the variations in CLD patients and relationship of different signs, symptoms or laboratory outcomes with the presence of SBP. OBJECTIVES: To assess the frequency of Spontaneous Bacterial Peritonitis and to analyse ascitic fluid and serum values of asymptomatic outpatients with cirrhotic ascites. METHODOLOGY: This is cross sectional study done among the Medicine OPD patients of CMCH, Coimbatore Hospital presenting with the cirrhosis and ascites. This study was conducted over 18 months (March 2018-March 2019) among 50 individuals. RESULTS: In this study, 48% of the subjects had cirrhosis due to alcohol followed by 24% due to HCV, 14% due to HCV & alcohol and 14% were cryptogenic. In this study, 68% of the subjects showed negative in their ascitic fluid culture. Of the remaining 32% who showed positive in their ascitic fluid culture, 16% showed Staph. aureus and 16% showed Staph. Viridians. 30% of the subjects showed negative for spontaneous bacterial peritonitis. Of the remaining 70% who showed positive for spontaneous bacterial peritonitis, 32% had culture positive neutrocytic ascites and 38% showed culture negative neutrocyticascites. 62% of the subjects were hospitalized and out of them 56% received cefotaxime antibiotic and 6% received Norfloxacin antibiotic. CONCLUSION: Among subjects with Child’s score class C, 100% subjects had SBP. Also there is significant relationship between Child’s score and SBP. Serum sodium, albumin, bilirubin, ascitic fluid protein and total leucocyte count were significantly different among the SBP patients and hence these values can be considered as early predicting markers of SBP in patients with cirrhosis.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 201711317 |
| Uncontrolled Keywords: | SBP (Spontaneous Bacterial Peritonitis), Ascitic Fluid Analysis, Alcoholism, HCV (Hepatitis C Virus), Child’s Score. |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 28 Jan 2021 18:24 |
| Last Modified: | 29 Jan 2021 03:31 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/13312 |
Actions (login required)
 |
View Item |
