Association and Impact of Thyroid Function on Non Alcoholic Fatty Liver Disease

Balaji, E (2020) Association and Impact of Thyroid Function on Non Alcoholic Fatty Liver Disease. Masters thesis, Coimbatore Medical College, Coimbatore.


Download (3MB) | Preview


BACKGROUND: The study focuses on the prevalence of hypothyroidism in patients with NAFLD (Non Alcoholic Fatty Liver Disease) and the complications developed due to low T3 and T4 levels. AIM OF THE STUDY: To investigate the Association and Impact of Thyroid function on Non-Alcoholic Fatty liver disease. OBJECTIVES: 1. To investigate the thyroid status of patients diagnosed with NAFLD. 2. To analyse the relationship and the trend of thyroid function with severity of Non-Alcoholic Fatty liver disease. PATIENTS AND METHODS: Our study included 100 patients who were diagnosed to have NAFLD based on Ultrasonography, Fibroscan and NAFLD fibrosis scoring and these patients were screened further for hypothyroidism using thyroid function tests. RESULTS: According to our study, nearly 46% of NAFLD patients had hypothyroidism according to the thyroid function tests. Out of these 46 percentage patients, nearly 24% had overt hypothyroidism and 22% had subclinical hypothyroidism. Hence, the prevalence of both subclinical and overt hypothyroidism was almost equal. CONCLUSION: All patients diagnosed to have NAFLD should undergo a routine screening for thyroid function at the time of initial diagnosis, as this prevents development of complications of hypothyroidism. Also, this prevents further progression of complications of NAFLD.

Item Type: Thesis (Masters)
Additional Information: 201711305
Uncontrolled Keywords: NAFLD (Non Alcoholic Fatty Liver Disease), Hypothyroidism, metabolic alterations, Diabetes Mellitus, AST (Aspartate aminotransferase), ALT (Alanine Aminotransferase).
Subjects: MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 28 Jan 2021 18:14
Last Modified: 29 Jan 2021 02:34

Actions (login required)

View Item View Item