A Study on Non-Invasive Predictors of Esophageal Varices in Cirrhosis

Santhanam, N (2020) A Study on Non-Invasive Predictors of Esophageal Varices in Cirrhosis. Masters thesis, Madurai Medical College, Madurai.

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Abstract

INTRODUCTION: Esophageal varices are porto-systemic collaterals and they form as a consequence of portal hypertension (a progressive complication of cirrhosis), preferentially in the sub mucosa of the lower esophagus. Rupture and bleeding from esophageal varices are major complications of portal hypertension and are associated with a high mortality rate. Variceal bleeding accounts for 10–30% of all cases of upper gastrointestinal bleeding. OBJECTIVE: The Main Goal of study is to predict Esophageal Varices in Cirrhotic Patients by Non Invasive Predictor {Compared with Endoscopy Finding}. METHOD OF STUDY: The Presence of Varices can be predicted by Low Platelet Count, Child Pugh Class B/C, Spleen Diameter, Portal Vein Diameter, Ratio Platelet Count and Spleenic Vein Diameter [Ratio PC/SD]. The Study will be conducted on 50 Patients admitted in General Medicine with Cirrhosis in Government Rajaji Hospital during the study period from May 2019 to October 2019. Clinical, Biochemical, Ultrasonographic Parameters Will Be Used .Esophageal Varices Will Be Graded By Endoscopy RESULTS: The Presence of Varices can be predicted by Low Platelet Count, Child Pugh Class B/C, Spleen Diameter. Our study P Value (0.001). CONCLUSION: The Presence of Varices can be Predicted by Low Platelet Count, Child Pugh Class B/C, Spleen Diameter. These Maybe Considered As Non Endoscopic Predictors For Diagnosis And Management of Varices.

Item Type: Thesis (Masters)
Additional Information: 201711118
Uncontrolled Keywords: liver function test (LFT), Aspartate aminotransferase (AST), Alanine transaminase (ALT).
Subjects: MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 28 Jan 2021 15:55
Last Modified: 28 Jan 2021 15:55
URI: http://repository-tnmgrmu.ac.in/id/eprint/13260

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