A Study on Non Invasive Imaging Approach of Palpable Breast Lumps

Ravichandran, S (2012) A Study on Non Invasive Imaging Approach of Palpable Breast Lumps. Masters thesis, Stanley Medical College, Chennai.


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INTRODUCTION: Breast cancer is the leading cause of non-preventable cancer deaths among women. Great strides in early detection and improved treatment have decreased breast cancer related deaths. A palpable mass in a woman's breast represents a potentially serious lesion and requires evaluation by history taking, physical examination and mammography. Mammography is a well-defined and widely accepted technique to evaluate clinically suspected breast lesions and screening for breast cancer. In these patients sonography is an useful adjunctive modality and helps characterizing a mammographically detected palpable abnormality, especially in patients with dense breast. Sensitivity and specificity of sonography or mammography is higher if sonography and mammography are combined. This dissertation titled ‘NON INVASIVE IMAGING APPROACH OF PALPABLE BREAST LUMPS’ was undertaken at Govt. Stanley Medical College, Chennai, between April 2010 and March 2011 to evaluate its role in the management of palpable abnormalities of the breast. AIMS AND OBJECTIVES: 1. To study that in cases of lump breast where mammogram and ultrasound breast do not show features of malignancy-FNAC is not necessary. 2. To evaluate the role of combined mammographic and sonographic imaging in patients with palpable abnormalities of the breast. 3. To provide systematic and practical approach to image evaluation of palpable breast masses and then evaluate its image charecterstics which help in decision making by clinician as to go for biopsy or lesion follow up. MATERIALS AND METHODS: Over a period of 12months, 50 patients aged 40 or above with palpable abnormalities of breast underwent combined mammographic and sonographic evaluation. RESULTS: 20 (40%) of the 50 palpable abnormalities had benign assessment, 12(60%) of the benign lesions were visible both on mammography and sonography; 7 (35%) of the 20 benign lesions were mammographically occult and identified at sonographic evaluation.1 lesion was sonographically occult (5%) and visualized on mammography. In 7(14%) of the 50 cases, imaging evaluation resulted in a suspicious assessment and all these lesions underwent biopsy and 2 were diagnosed as having malignancy. 23(46%) of the 50 palpable abnormalities had negative imaging assessment finding: of these 9 patients underwent biopsy and all had benign findings. The sensitivity and negative predictive value for combined mammographic and sonographic assessment were 100%; the specificity was 80.1%. CONCLUSION: Cancer was diagnosed in only 2 of the 50 women who underwent combined imaging for palpable abnormalities of the breast. Combined mammographic and sonographic assessment was shown to be very helpful in identifying benign as well as malignant lesions causing palpable abnormalities of the breast.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Biopsy, breast, mammography, palpable lumps, sonography.
Subjects: MEDICAL > General Surgery
Depositing User: Subramani R
Date Deposited: 14 Sep 2020 18:20
Last Modified: 14 Sep 2020 18:20
URI: http://repository-tnmgrmu.ac.in/id/eprint/13155

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