Rajeswaran, A (2012) The Clinical study on Factors Influencing Outcome of Disease in Gastro Duodenal Perforations. Masters thesis, Coimbatore Medical College, Coimbatore.
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Abstract
Gastro duodenal perforations following peptic ulcer disease (PUD) is one of the most common surgical emergency encountered in surgical practice. Aim of the Study to find the factors influencing outcome of disease, prognosis of the disease and surgery and followed up for six months for complications. By this study able to improve the outcome of disease by reducing the morbidity and mortality. In our study we included 50 patients who operated for Gastro duodenal perforations and studied the risk factors which influence of outcome of disease in view of morbidity and mortality. The factors included in the study where Age, Sex, Age of perforations (<24/>24 hrs.), Site of perforations (gastric/Duodenal), Size of perforations (<1/1-2/>2 cms), Presence or absence of shock(systolic BP<100 mm hg), Medical comorbidities- Respiratory infection, DM, SHT and IHD, Patient taking NSAID, Smoker and Consumer of alcohol, and analysed with outcome of patients. Statistical and analysis was done using Fisher Exact Test (Two Tailed) to find the significance of proportion of incidence of complication in association with risk factors. And we found Mean age of PPU is 45.34, the gastro-duodenal perforations is the disease of the male preponderance, but the incidence in female is increasing, Gastric perforations has the poor outcome, but in our study not showed significance. In our study we found the following factors were significantly increases the morbidity and mortality- Age >60 yrs, Size of perforations >2 cms, Delayed presentation >24 hrs, Patient presented with shock (BP<100 mm of Hg), Concominant medical illness, Smoking. Most important set back of this study is the study of H. Pylori is not included. The following factors were not significantly affect the outcome of disease in view of mortality and morbidity, in our study - Sex of the patient, Site of perforation, H/o alcohol consumption, H/o NSAID ingestion.
| Item Type: | Thesis (Masters) |
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| Additional Information: | Reg.No.22091218 |
| Uncontrolled Keywords: | Factors Influencing Outcome, Gastro Duodenal Perforations, Clinical study. |
| Subjects: | MEDICAL > General Surgery |
| Depositing User: | Subramani R |
| Date Deposited: | 14 Sep 2020 18:04 |
| Last Modified: | 15 Sep 2020 15:26 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/13150 |
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