Annu Susan George, (2012) An Analysis of Cardiac Function in Chronic Obstructive Pulmonary Disease. Masters thesis, Coimbatore Medical College, Coimbatore.
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Abstract
BACKGROUND: Chronic obstructive pulmonary disease has many cardiovascular effects which are the main contributors to the increased morbidity and mortality. AIM OF THE STUDY: To evaluate COPD patients clinically, assess their cardiac function by means of ECG and Echocardiography, and correlate disease severity with 6 minute walk distance and BODE index. MATERIALS AND METHODS: A total of 50 patients with COPD were selected, staged by GOLD criteria and evaluated clinically, radiologically and with ECG and echocardiography. 6 minute walk test was done and BODE scores calculated. RESULTS: A significant correlation was observed between GOLD severity staging and development of ECG features of cor pulmonale(p <0.05) and between BMI and 6MWD (p< 0.001).Echocardiography showed measurable TR in 72% with grade 3 TR IN 22% of patients .TAPSE < 18 mm was observed in 28% of patients . In 48% there was no PH (RVSP< 40 mmHg), 26% had mild PH (RVSP 40- 50 mmHg), 8% had moderate PH (RVSP 50- 60 mmHg) and 18% had severe PH (RVSP> 60 mmHg). CONCLUSION: PH is the major cardiac complication in COPD patients, which ultimately leads to cor pulmonale. BODE Index is a reliable indicator of severity of COPD and also of cardiac involvement, particularly right ventricular dysfunction. ECG and Echocardiography are essential in the comprehensive evaluation of cardiac status in COPD patients.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 20091212 |
| Uncontrolled Keywords: | COPD, PH, Cor pulmonale, ECG, Echocardiography, BODE index, 6MWD, TAPSE, RVSP. |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 12 Sep 2020 16:29 |
| Last Modified: | 12 Sep 2020 16:29 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/13109 |
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