A Study on Lipid Profile in Hypertension Patients

Balaji, G (2012) A Study on Lipid Profile in Hypertension Patients. Masters thesis, Stanley Medical College, Chennai.

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Abstract

BACKGROUND: Hypertension and dyslipidemia are independent risk factors for atherosclerosis. Hypertension is often associated with hyperlipidemia as shown in various studies. Understanding the relationship between hypertension and hyperlipidemia will help in in better assessment of risk factors for atherosclerotic arterial disease. METHODS: In this study 100 hypertensive patients were selected and their fasting lipid profile was taken. The parameters done were total cholesterol, triglycerides, LDL, VLDL, HDL, TC/HDL ratio, LDL/HDL ratio. The values were compared based on parameters like age, gender, obesity, smoking, CVA, IHD etc. among hypertensive patients. These values were also compared with values obtained from healthy controls with out hypertension. RESULTS: In the hypertension patients total cholesterol, LDL, VLDL, triglycerides, TC/HDL, ratio, LDL/ HDL ratio was elevated when compared to controls which was statistically significant. The HDL levels were significantly low in hypertension patients compared to controls. Among hypertensive patients with obesity, total cholesterol, LDL, triglycerides were significantly elevated. In IHD patients total cholesterol, LDL, triglycerides were significantly high. total cholesterol, triglycerides were significantly elevated in the CVA and hypertension. In smokers, the toal cholesterol, LDL, VLDL, TC/HDL ratio, LDL/HDL ratio are significantly elevated compared to non smoking hypertensive patients. INTERPRETATION AND CONCLUSION: The study shows that the hypertension patients have significantly elevated levels of total cholesterol, LDL, VLDL, triglycerides, compared to non smokers. The HDL levels were significantly low in hypertension patients compared to healthy controls. Hypertension patients with associated condition such as obesity, CVA, IHD, Smoking have abnormal lipid levels compared to hypertensive patients without these conditions.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Hypertension, hyperlipidemia, total cholesterol, HDL, VLDL, LDL, triglycerides, LDL, HDL ratio, TC/HDL ratio, cerebrovascular accident, ischemic heart disease, obesity.
Subjects: MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 12 Sep 2020 15:46
Last Modified: 12 Sep 2020 15:46
URI: http://repository-tnmgrmu.ac.in/id/eprint/13108

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