A study on the correlation between clinical outcome and residual prostatic weight ratio after transurethral resection of prostate for benign prostatic hyperplasia

Senthil, D (2012) A study on the correlation between clinical outcome and residual prostatic weight ratio after transurethral resection of prostate for benign prostatic hyperplasia. Masters thesis, Madras Medical College, Chennai.

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Abstract

INTRODUCTION: TURP is the gold standard management for BPH and is standardized procedure across the globe. Still there is no literature to suggest the amount of tissue to be resected for optimal clinical outcome. AIM OF THE STUDY: Aim is to determine whether the residual prostatic weight ratio has an impact on the outcome following transurethral resection of prostate (TURP) for Benign Prostatic Hyperplasia (BPH). MATERIAL & METHODS: All patients with BPH planned for TURP were included in the trial. After appropriate exclusion criteria, 100 patients were enrolled. Pre operative parameters like IPSS score, QOL index, Peak flow rate and PVR were recorded. During TURP, the resected weight of the prostatic chips was measured and the residual prostatic weight calculated. Patients were stratified into two groups based on value of this RPWR as <50% and >50%. Patients were followed up post operatively and improvement in the parameters mentioned were compared among the two groups. RESULTS: Of the total 100 patients, 65 had RPWR of <50% and 35 had RPWR of >50%. The IPSS score, QOL index, PFR and PVR showed significant improvements in all patients. Comparing the improvement in parameters between the two groups, the difference in group-1 (RPWR<50%) was significantly more than in group-2 (RPWR>50%). The p value for IPSS score was 0.04 and that for PFR was <0.001. The difference in improvement in QOL and PVR were not significant. CONCLUSION: The clinical improvement in IPSS score and peak flow rate were significantly more in patients with residual prostatic weight <50%. Hence, resection of more amount of tissue during TURP results in better clinical outcome.

Item Type: Thesis (Masters)
Uncontrolled Keywords: TURP, Residual Prostatic Weight Ratio(RPWR), Clinical outcome after TURP.
Subjects: MEDICAL > Urology
Depositing User: Subramani R
Date Deposited: 11 Sep 2020 16:23
Last Modified: 11 Sep 2020 16:23
URI: http://repository-tnmgrmu.ac.in/id/eprint/13105

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