Kanmani, D (2016) A Study of Expression of Epidermal Growth Factor Receptor(EGFR) and Vascular endothelial growth factor (VEGF) in Epithelial Ovarian Neoplasms. Masters thesis, Madras Medical College, Chennai.
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Abstract
Ovarian carcinoma is the 6th most common carcinoma among women in the world and forms 1.7 to 8.7% of female cancers in India. It is the most common cause of gynecological cancer death in women. Surface epithelial ovarian carcinoma accounts for 90 to 95% of ovarian malignancies. EGFR and VEGF both have diagnostic and therapeutic implications. Both markers were found to be independent prognostic factors in ovarian neoplasms. This is just a hospital based study that may not reflect the exact occurrence in the community as a whole. There is a wide arena of community based studies and research activities being carried out with these two markers - opening up newer dimensions and horizons in the ‘early diagnosis’ and 79 ‘chemotherapeutic approaches’ with anti EGFR and VEGF antibodies in the battle against this ‘silent killer’ called ‘Cancer Ovary’.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Surface epithelial ovarian carcinoma ; Epidermal Growth Factor Receptor(EGFR) ; Vascular endothelial growth factor (VEGF) ; Immunohistochemical analysis ; Bevacizuma. |
| Subjects: | MEDICAL > Pathology |
| Depositing User: | Laksham S |
| Date Deposited: | 10 Jul 2017 07:55 |
| Last Modified: | 08 Nov 2018 07:52 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/1286 |
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