Lavanya, A (2012) Anti–Ulcer activity of Kozhiavarai Ilai Chooranam (Canavalia Virosa.(Roxb),W&A) & Hepatoprotective activity of “Vengara Chunnam”. Masters thesis, Government Siddha Medical College, Chennai.
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Abstract
ANTI –ULCER ACTIVITY OF KOZHIAVARAI ILAI CHOORANAM: The herb Kozhiavarai ilai was collected from Rarapuram, Pudukkottai (Dt) and purified then powered and stored. This drug was subjected to various studies by the author. ❖ Kozhiavarai ilai Chooranam was selected for this study to evaluate the Anti – ulcer activity, and to prove its efficacy and safety in peptic ulcer disease. ❖ To collect the information about the drug, various text books, Literature were referred. From them, the author came to an idea about the drug and its efficacy on Peptic ulcer. ❖ A brief description about botanical aspect of the herb Kozhiavarai ilai and its identifying characters and Phyto chemical data’s were given. ❖ The pharmacological analysis showed that the drug has got significant Anti ulcer activity. ❖ In clinical study, the drug has showed marked improvement in 74% of cases. ❖ The patients were responding well from the beginning of the treatment and no adverse effects were reported. ❖ This present study suggests that Kozhiavarai ilai Chooranam has the remarkable medicinal value against the disease Peptic ulcer without any adverse effect. CONCLUSION: The trial drug of “Kozhiavarai ilai Chooranam” has been selected and its efficacy was analyzed in the treatment of Peptic ulcer. ❖ The drug is easily available and preparation is very simple. ❖ The trial medicine is cost effective. ❖ The drug shows good Anti Ulcer activity. ❖ No adverse effects were produced during the entire clinical trial. ❖ From the above observation, I conclude that the drug “Kozhiavarai ilai chooranam” (Canavalia virosa) gives a new hope in the field of Peptic ulcer Treatment. HEPATOPROTECTIVE ACTIVITY OF “VENGARA CHUNNAM”: The herbo mineral drug Vengara chunnam was prepared as per the sasthric way. ❖ This drug was subjected to various studies by the author. Vengara chunnam was selected for this study to establish the safety and efficacy of its Hepatoprotective activity on Kamalai. ❖ To collect the information about the drug, various text books, Literature were referred. From them, the author came to an idea about the drug and its efficacy on Kamalai. ❖ A brief description about modern aspect and Siddha aspect of the mineral Vengaram and its identifying characters and Physico – chemical data’s were given. ❖ The Physico – chemical analysis shows the precence of Potassium, Phospharous, Boron, Iron, Calcium, Magnesium, Sodium, and Sulphur. These elements are useful in many metabolic functions of our body. ❖ Acute and Sub acute toxicological studies show strong evidence of the nontoxic effect of the Vengara chunnam. The results showed Vengara chunnam is safe and explained the extensive utilization of the Siddha medicine. ❖ The pharmacological analysis showed that the drug has got significant Hepatoprotective Efficacy. ❖ In clinical study, the drug has showed improvement in 64% of cases. ❖ The patients were responding well from the beginning of the treatment and no adverse effects were reported. This present study suggests that Vengara chunnam has remarkable medicinal value against the disease Kamalai. CONCLUSION: Vengara chunnam is a unique type medicine, which is made up by a special type of preparation method mentioned in Siddha research Pharmacopia. ❖ Literature survey, Physico chemical anatysis, Chemical analysis, was showed the efficacy of Vengaram (Borax) related to Liver diseases. Latex of Argemone mexicanai Linn is also having the traditional usage in treatement of liver diseases. ❖ The finding of the pre clinical study suggests that effective role of Vengara Chunnam on fatty liver disease with fatty infiltration of liver with inflammation and hepatic necrosis to cirrhosis. ❖ Vengara Chunnam had remarkable effect on lipid with complete reduction in the lipid factors in the liver and its related enzymes.The metalloid drug could play similar role as extracellular calcium and it could evidence effective hepatoprotective drug. ❖ Significant efficacy of the drug its human dose prescribed in the siddha literature evidences only therapeutic efficacy rather preventive role.It may be suggested as a drug to fatty liver which finds negligence cure in modern medicine. ❖ This can be a definite alternative drug to modern allopathic drug in fatty liver. The study reveals the possible mechanism of action on lipid lowering effect with potential anti oxidative role. ❖ In clinical trials, the drug shows the significant improvement of 64% in Hepato cellular diseases. ❖ Thus the innovative siddha science based vengara chunnam had been proved by the modern scientific mechanism as a simple remedy to the complicated metabolic disorder in modern era.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | Reg.No.32091603 |
| Uncontrolled Keywords: | Anti–Ulcer activity, Kozhiavarai Ilai Chooranam, Canavalia Virosa.(Roxb),W&A, Hepatoprotective activity, Vengara Chunnam. |
| Subjects: | AYUSH > Gunapadam |
| Depositing User: | Subramani R |
| Date Deposited: | 12 Aug 2020 15:41 |
| Last Modified: | 12 Aug 2020 15:41 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/12820 |
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