A study of efficiency of autologous platelet rich plasma in myringoplasty.

Kumar, R V (2013) A study of efficiency of autologous platelet rich plasma in myringoplasty. Masters thesis, Kilpauk Medical College, Chennai.


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Chronic suppurative otitis media is defined as chronic inflammation of the mucoperiosteal lining of the middle ear cleft. It is associated with a persistent or intermittent infected discharge through a non intact tympanic membrane. It is prevalent in developing countries like India and is more common in lower socio economic groups. The incidence is very high among rural population than in urban population. The overall prevalence rate is 46 and 16 persons per thousand in rural and urban population. Chronic otitis media (COM) is the term that equates with classic term “chronic suppurative otitis media” which is no longer advocated as there is no pus in all case of chronic otitis media. They are now divided into active COM where there is production of pus and inactive COM where there is no pus but can become active at times. In our study out of the 50 patients who underwent surgery, 30 were females (60 percent) and 20 (40 percent) were males. This is in contrast to UK national study of hearing; according to them the incidence is equal in both male and female. Our study concludes the following: Platelet rich plasma is a cheap and cost effective platelet concentrate with enriched growth factors, it accelerates the tympanic membrane closure following myringoplasty, it prevents graft migration. It improves the overall success rate of myringoplasty, it has no noticeable side effects.

Item Type: Thesis (Masters)
Uncontrolled Keywords: autologous platelet rich plasma; myringoplasty; Chronic suppurative otitis media
Subjects: MEDICAL > Otolaryngology
Depositing User: Devi S
Date Deposited: 10 Jul 2017 07:02
Last Modified: 31 Mar 2018 07:49
URI: http://repository-tnmgrmu.ac.in/id/eprint/1280

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