Nandhagopal, K (2012) Anti-Diabetic Activity of Karchure Chooranam (Phoenyx Dactylifera.Linn) & Analgesic and Anti Arthritic Activity of “Rasa Mezhugu”. Masters thesis, Government Siddha Medical College, Chennai.
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Abstract
ANTI-DIABETIC ACTIVITY OF KARCHURE CHOORANAM: Karchure Chooranam was selected by the author for this study to establish the Anti-Diabetic activity. To collect the information about the drug, various text books, literature were referred. From them, the author came to an idea about the drug and its efficacy on Diabetes Mellitus. The trial drug Karchure was collected from TAMPCOL outlet store and Fruit market of Tambaram at Chennai. It was identified and authenticated and then purified, processed powdered and stored. This drug was subjected to various studies by the author. A brief description about botanical aspect of the dry fruit karchure and its identifying characters and Phyto chemical data’s were given. The Phyto chemical analysis of the drug shows that it contains Potassium, Calcium, Zinc, Magnesium, Iron, and Tannins, Phlobatannins, Phenolic Compounds, Flavonoids and Cardiac Glycosides. It is related in treatment of Diabetes Mellitus. The preclinical study showed that the drug has got safety and significant Anti diabetic activity. The patients were responding well from the beginning of the treatment and no adverse effects were reported. The clinical result reveals that 73% of patients were having 75% of improvement in the clinical futures and biochemical reports. This present study confirms that Karchure Chooranam has the remarkable Antidiabetic activity and high therapeutical value against the disease Diabetes Mellitus. In my further studies I want to find out the exact targeting molecule of Karchure chooranam that triggers the Hypoglycaemic effect in Diabetics. ANALGESIC AND ANTI ARTHRITIC ACTIVITY OF “RASA MEZHUGU”: Rasa Mezhugu was selected by the author for this study to establish the analgesic and anti arthritic activity. To collect the information about the drug, various text books, literature were referred. From them, the author came to an idea about the drug and its efficacy on Rheumatoid Arthritis. The mercury used in this preparation is derived from lingam as the purest form of mercury, Vaalai Rasam is used. Then all the other drugs were purchased and duly authenticated and then subjected to preparation. The Phyto chemical analysis of the drug shows that it contains Calcium, Iron, and Tannins, Alkaloids, Steroids, Phlobatannins, Phenolic Compounds, Flavonoids and Cardiac Glycosides. It is related in treatment of Rheumatoid Arthritis. The preclinical study showed that the drug has got safety and significant Analgesic and Anti- arthritic activity. The patients were relieved well from the signs and symptoms gradually and no adverse effects were reported. The clinical result reveals that 67% of patients were having 75% of improvement in the clinical futures and biochemical reports. This present study confirms that Rasa Mezhugu has the remarkable Analgesic and Anti- arthritic activity and high therapeutical value against the disease Rheumatoid Arthritis. This must be involved to further studies to explorate the exact target activity and the responsible compound identification and for standardization.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | Reg.No.32091604 |
| Uncontrolled Keywords: | Anti-Diabetic Activity, Karchure Chooranam, Phoenyx Dactylifera.Linn, Analgesic and Anti Arthritic Activity, Rasa Mezhugu. |
| Subjects: | AYUSH > Gunapadam |
| Depositing User: | Subramani R |
| Date Deposited: | 02 Aug 2020 15:24 |
| Last Modified: | 02 Aug 2020 15:24 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/12722 |
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