Diuretic and Nephroprotective Activity of Avuri Kudineer (Indigofera Tinctoria.Linn) & Analgesic and Anti-Arthritic Activity of Velvanga Chunnam

Priyadarsini, G (2012) Diuretic and Nephroprotective Activity of Avuri Kudineer (Indigofera Tinctoria.Linn) & Analgesic and Anti-Arthritic Activity of Velvanga Chunnam. Masters thesis, Government Siddha Medical College, Chennai.

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Abstract

DIURETIC AND NEPHROPROTECTIVE ACTIVITY OF AVURI KUDINEER: The evaluation of the efficacy of the single drug of ‘Avuri kudineer’ for diuretic and nephroprotective activity in the managements of oedema, urolithiasis and hypertension gave significant results. The presence of terpenoids and cardiac glycosides and the inorganic constituents enhance the activity of the diuretic activity.The presence of carbohydrates increases the solubility of the cardiac glycosides content.Hence this kudineer content enhances the diuretic activity. Pharmacological animal studied strengthens the study and acts as potent diuretic comparable to that of standard drug and spared the potassium loss in urine.Also protects the kidney from cisplatin induced damage which revealed the diuretic and anti-oxidant nature of ‘Avuri kudineer’. Clinically, the drug relieved the symptoms of SHT, Urolithiasis, oedema and showed net increase in 24 hrs urine output. No adverse reactions were produced during the period of the clinical study. In total, avuri act as diuretic agent and can be applicable to the conditions which needs diuretic demands. In addition it can also be given to the cancerous patients under the treatment of cisplatin since it showed chemopreventive effect against it and can be studied in future studies. ANALGESIC AND ANTI-ARTHRITIC ACTIVITY OF VELVANGA CHUNNAM: The trial drug of “Velvanga Chunnam ” has been selected and its efficacy was analyzed in the treatment of Rheumatoid arthritis.The drug is easily prepared and preparation is very simple when compared to modern drugs.The trial medicine is cost effective. It contains essential elemental, organic, constituents for its basic and potentiality and it represented the nano particles of its content. The drug shows good Analgesic and Anti-Arthritic activity which was mediated through anti-oxident activity. All the patients of RA showed significant reduction of the symptoms in terms of pain, swelling of the joints, morning stiffness, and restricted ROM. The ESR values are also greatly reduced and moved towards normalcy. There were no adverse effects of the Velvanga chunnam during treatment duration. The general conditions of the body was also felt better. Increase in urine output,reduction of the body tiredness and improvement of movements of the joints were also improved. Some patients of very long duration showed moderate significant effect in terms of pain, but swelling was reduced in the joints. The trial drug of “Velvanga Chunnam” has been selected and its efficacy was analyzed in the treatment of Rheumatoid arthritis. No adverse effects were produced during the entire clinical trial. From the above clinical observation, I conclude that the drug “Velvanga chunnam” gives a new hope in the field of Rheumatoid Arthritis Treatment might through anti-oxidant mediated analgesic and anti-arthritic activity.

Item Type: Thesis (Masters)
Additional Information: Reg.No.32091605
Uncontrolled Keywords: Diuretic and Nephroprotective Activity, Avuri Kudineer Indigofera Tinctoria.Linn, Analgesic and Anti-Arthritic Activity, Velvanga Chunnam.
Subjects: AYUSH > Gunapadam
Depositing User: Subramani R
Date Deposited: 02 Aug 2020 15:09
Last Modified: 02 Aug 2020 15:09
URI: http://repository-tnmgrmu.ac.in/id/eprint/12721

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