Sathya, S (2012) A Study on Venpadai. Masters thesis, Government Siddha Medical College, Chennai.
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Abstract
Venpadai has been chosen for the dissertation work by the author. ❖ Various literatures dealing with Venpadai have been collected from Siddha and modern text books. ❖ 40 Patients of both sexes of various adult age groups satisfying the inclusion and exclusion criteria were selected. All necessary investigation was done for them and photographs of the lesion were taken. ❖ A day before starting the trial treatment, neutralizing the mukkutram by purgation, it will be carried out by Agasthiyar Kuzhambu-100mg, early morning with hot water. All the patients were treated with trial medicines are 1. Erimugi Chooranam, 2. Kantangkathiri Pazha Thylam. ❖ The results obtained from the studies are summarized below: 1. Female (57.5%) were affected more than males (42.5%) 2. The cases were noted in the age group ranging from 10-70yrs. 3. Middle (52.55%) and Lower (35%) classes were more affected than upper classes (12.5%) 4. High incidence of Venpadai found to be more in neithal thinai (65%) and kaar kaalam (50%). ❖ On Examination of Uyir thathukkal the following were deranged in more number of cases. In Vatham: viyanan (25%), Praanan, Abaanan and Koorman(12.5%) were affected. In Pitham: Prasagam (100%), Ranjagam (50%), Alosagam (12.5%) were affected. In Kabam: Avalambagam (12.5%), Santhigam (25%) were affected. ❖ In Udal Kattugal: Saaram (100%), Senneer (50%), Kozhuppu (25%), Enbu (25%) were affected ❖ In Enn Vagai Thervu: Niram (100%), Naa (12.5%), Vizhi (12.5%), Malam (12.5%) Moothiram (17.5%) were affected. ❖ The patients responded to the trial medicines showing Among 40 patients 31patients are improved from this disease which has been noted as appearance of enormous repigmented spots in affected areas.Rest of the 9 patients had slight repigmention. ❖ Among 4 patients 2 of them had improvement in the colour change of the hair from gray or white to normal colour of the hair. ❖ The Chemical studies of the trial drugs possess Phosphate, Iron, Zinc, Calcium, Potassium, Starch, Alkaloid, Tannic acid. ❖ The drug also subjected to pharmacological and toxicological tests in rat models. The results revealed that the drug had very effective results. There were no signs of toxicity as could be judged by the absence of undesirable clinical manifestations. ❖ The bio-statistical report of the clinical trial shows significant result. CONCLUSION: Venpadai may occur due to various causes and it leads to mental stress and strain. Hence it is one of the causes of psychosomatic disorder. When the trial drug Erimugi Chooranam (Internal) with Kantangkathiri Pazha Thylam (External) were administered to the Venpadai patients, it showed improvement in varying degrees in all the cases. ❖ The trial medicine Erimugi Chooranam predominating with Kaippu, Inippu Suvai respectively neutralizes the Pitham. ❖ More over in Venpadai Pitha Kuttram is affected. The affected Kuttram is neutralized by Kaippu Suvai thereby the drug act on Ethirurai. ❖ In Chemical Analysis the trial medicine contain Iron, it is very essential to induce erythropoiesis. ❖ From the preclinical study Erimugi Chooranam increase the haemoglobin level. ❖ The Erimugi Chooranam does not produce any toxicilty in preclinically. So it is non toxic and safe drug for Venpadai. ❖ No adverse effects were noticed during treatment period. The ingredients of Erimugi Chooranam are of plants easily available and harmless to human beings. ❖ From this clinical studies, I conclude that the trial medicines which gives a 60-65% of improvement within minimum of 45 days to maximum of 90 days of treatment. Further continuation of this medication for prolonged period of time may give complete cure in Venpadai.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | Reg.No.32091107 |
| Uncontrolled Keywords: | Venpadai, Vitiligo, Qualitative analysis, Erimugi Chooranam. |
| Subjects: | AYUSH > Maruthuvam |
| Depositing User: | Subramani R |
| Date Deposited: | 01 Aug 2020 17:33 |
| Last Modified: | 07 Aug 2020 02:55 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/12704 |
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