Suganya, M (2017) Prevalence and Clinical features of respiratory syncytial virus infection in children less than 60 months of age hospitalized with severe pneumonia in a tertiary care referral hospital: A Cross-sectional and analytical study. Masters thesis, Madras Medical College, Chennai.
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Abstract
BACKGROUND: Viruses are common pathogens of acute lower respiratory tract infections in children. Among the viral pathogens RSV is the most common causative agent. This study aims to estimate the prevalence and clinical profile of RSV severe pneumonia in children less than 60 months of age hospitalised in a tertiary care hospital. METHODS: We included 100 children less than 60 months of age admitted with a diagnosis of severe pneumonia in general ward at Institute of child health & hospital for children,Chennai, Tamil Nadu. Nasopharnygeal aspirate were collected from the study group and subjected to RT-PCR for RSV detection. Data were simultaneously collected to analyse the clinical profile of children in the study group. RESULTS: The prevalence of RSV infection in our study population was 30%. In the RSV positive group the mean age was 11 months. The male to female ratio in the incidence of RSV was5 : 1. Underlying congenital heart disease & family history of allergies were identified as risk factor for RSV severe pneumonia in our study. The most common presenting complaint in RSV infection were fever, cough, running nose and vomiting. The mean duration of hospital stay was 5.04 days. Need for oxygen support and mechanical ventilation were not statistically different between RSV and non RSV severe pneumonia. CONCLUSION: Respiratory syncytial virus was a common cause of severe pneumonia in children less than 60 months of age. High risk groups include children with underlying heart disease and family history of allergies. The development of novel prevention and treatment strategies should be accelerated as a priority.
| Item Type: | Thesis (Masters) |
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| Additional Information: | Reg.No.201417003 |
| Uncontrolled Keywords: | Respiratory syncytial virus, severe pneumonia, RT-PCR, risk factors, oxygen and mechanical ventilation. |
| Subjects: | MEDICAL > Paediatrics |
| Depositing User: | Subramani R |
| Date Deposited: | 23 Jul 2020 17:39 |
| Last Modified: | 23 Jul 2020 17:39 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/12673 |
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