Association of Lichen Planus with Metabolic Syndrome

Sumithra, S (2017) Association of Lichen Planus with Metabolic Syndrome. Masters thesis, Madurai Medical College, Madurai.


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INTRODUCTION: Lichen planus (LP) is a papulosquamous disorder involving the skin, nails, hair follicles and mucous membranes. It has a chronic course with relapse and period of remission1. The disease was first described by Hebra as Leichen ruber. Erasmus Wilson, in 1869 named the condition as leichen planus. The skin, hair, nails, mucus membrane may be affected. Lichen Planus is rare in children. Common in middle aged adult. Itching is variable. The primary lesion is violaceous flat topped papule with several clinical forms. AIM OF THE STUDY: To find the association of lichen planus with metabolic syndrome. MATERIALS AND METHODS: A total of 113 newly diagnosed lichen planus patients were included in the study to find the association with metabolic syndrome. Children below 10 years were excluded. Detailed history was taken, Systemic examination and dermatological examination were done. Blood pressure and waist circumference were measured at the time of examination. Blood sugar, triglyceride and high density lipoprotein were taken after 8 hours of fasting. International diabetic federation criteria 2015 was used to diagnose metabolic syndrome in the lichen planus patients. RESULTS: Metabolic syndrome was high in females when compared to males. Prevalence of with metabolic syndrome in the 4th decade was significantly higher with 57.1% compared to other age group. When compared to classical variant, which was common and reported in 72 cases, eruptive variant had association with metabolic syndrome with p value of 0.008 which was significant. CONCLUSION: Lichen planus in female patients presented in 4th decade had more association with metabolic syndrome. Among the variants, eruptive variant of lichen planus was associated more with metabolic syndrome. Cases not associated with metabolic syndrome, many of them had dyslipidemia.

Item Type: Thesis (Masters)
Additional Information: Reg.No.201430102
Uncontrolled Keywords: Lichen planus, eruptive, metabolic syndrome.
Subjects: MEDICAL > Dermatology Venereology and Leprosy
Depositing User: Subramani R
Date Deposited: 22 Jul 2020 14:31
Last Modified: 22 Jul 2020 15:02

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