Sobana, E (2017) A Study on Variation in Co-Morbidity and Clinical Profile according to Symptom Dimensions in Obsessive Compulsive Disorder. Masters thesis, Madras Medical College, Chennai.
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Abstract
BACKGROUND: The complex heterogeneous clinical phenotype of obsessive–compulsive disorder (OCD) can be summarized into a few temporally stable and consistent symptom dimensions that may have distinct clinical and neurobiological correlates. The frequent co-occurrence of OCD with other psychiatric disorders and the relatively specific association patterns between OCD symptom dimensions and co-morbid disorders support the importance of OCD sub-typing for treatment, genetic, and other research studies of this heterogeneous disorder. However the clinical utility of identifying such symptom dimensions remains somewhat unclear. This study is to throw light regarding clinical utility of symptom dimensions. AIM OF THE STUDY: To study the relationship between symptom dimensions and various factors like socio-demographic, disorder related, symptom severity, psychiatric co-morbidities, insight, suicidality, quality of life for obsessive compulsive disorder. METHODS: A cross sectional study was conducted on 50 OCD patients using YBOCS Symptom checklist and severity scale and also the relationship between symptom dimensions with comorbidity and various clinical profile has been assessed. RESULTS: Sexual dimension was more in educated group whereas aggressive dimension was more in uneducated group. Checking/ doubting dimension had lowest severity rating. Mixed and sexual dimensions had low psychological quality of life whereas contamination dimension had low physical quality of life. Mixed dimension had many of them having suicidal aspect of not feeling worthy. Among those who lacked insight 75% belonged to mixed dimension. Difference in level of anxiety among dimensions. More the mean duration of OCD more the aggressive dimension. Mixed dimension had more family history of OCD. CONCLUSION: Our study demonstrates relatively specific associations between OCD symptom dimensions and clinical characteristics supporting the view that symptom dimensions could be employed to reduce the heterogeneity of OCD. The study encourages and supports inclusion of symptom dimensions in characterizing OCD.
| Item Type: | Thesis (Masters) |
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| Additional Information: | Reg.No.201428005 |
| Uncontrolled Keywords: | Obsessive compulsive Disorder, Yale Brown Obsessive Compulsive Scale (Y-BOCS), symptom dimensions, comorbidity. |
| Subjects: | MEDICAL > Psychiatry |
| Depositing User: | Subramani R |
| Date Deposited: | 21 Jul 2020 10:49 |
| Last Modified: | 21 Jul 2020 10:49 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/12629 |
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