A Comparative study of Epidural Administration of 0.25% Bupivacaine Versus 0.25% Bupivacaine+8mg Dexamethasone on Postoperative Analgesia following Gynaecology Surgery

Mahendiravarman, K (2017) A Comparative study of Epidural Administration of 0.25% Bupivacaine Versus 0.25% Bupivacaine+8mg Dexamethasone on Postoperative Analgesia following Gynaecology Surgery. Masters thesis, Stanley Medical College, Chennai.

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Abstract

After getting ethical committee approval the study was conducted in 60 patients undergoing gynaecological procedures belonging to ASA physical status 1 &2. The 60 patients enrolled in the study were divided into two groups. The data were statistically analysed, compared and discussed. The results obtained are summarised below: 1. The demographic data like age,weight and height were comparable to each other in both the groups. 2. Time for first anaelgesic request was significantly earlier in group BS patients receiving normal saline (2.27 hrs) and it was delayed in dexamethasone receiving group (3.53)hrs. 3. The duration of analgesia was significantly prolonged in group in BD patients receiving dexamethasone (351.53) when compared to group BS patients receiving normal saline (260.50). 4. Regarding side effects two patients receiving dexamethasone had hypotension. This was treated with fluid bolus and single dose of injection ephedrine 6mg iv and hypotension wasn’t found in patients receiving normal saline. 5. There is nil incidence of nausea and pruruitus in both the groups. CONCLUSION: We conclude that epidural administration of dexamethasone – bupivacaine admixture resulted in better postoperative analgesia in terms of lower postoperative pain score, prolonged postoperative analgesia and patient comfort with fewer side effects when compared with the other two groups. We also conclude that this resulted in prolonged postoperative analgesia without any side effects like nausea, pruritus except hypotension in few patients.

Item Type: Thesis (Masters)
Additional Information: Reg.No.201420054
Uncontrolled Keywords: Epidural Administration, 0.25% Bupivacaine, 0.25% Bupivacaine+8mg Dexamethasone, Postoperative Analgesia, Gynaecology Surgery.
Subjects: MEDICAL > Anaesthesiology
Depositing User: Subramani R
Date Deposited: 21 Jul 2020 03:06
Last Modified: 21 Jul 2020 03:06
URI: http://repository-tnmgrmu.ac.in/id/eprint/12605

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