A Study on the Difference between Risk Factors of Anterior and Posterior Circulation Stroke in Adults

Aravindh, M (2013) A Study on the Difference between Risk Factors of Anterior and Posterior Circulation Stroke in Adults. Masters thesis, Madurai Medical College, Madurai.


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INTRODUCTION: In adult life, stroke rank first amongst the diseases of the nervous system. Anterior circulation stroke is the commonest stroke type, whereas stroke occurring in posterior circulation forms only 20%. The internal carotids systems and their branches form the anterior circulation of the brain. The majority of both cerebral hemispheres are supplied by both carotids except the medial part of the temporal lobes, and occipital lobes which are supplied by the posterior cerebral arteries. Two vertebral arteries, one basilar artery and two posterior cerebral arteries and their branches form the posterior circulation of brain vascular supply. The area of brain supplied by the posterior circulation includes medial temporal lobe, brainstem, cerebellum, occipital lobes and thalamus. AIMS AND OBJECTIVES 1. To study the risk factor prevalence in anterior circulation stroke in adults. 2. To study the risk factor prevalence in posterior circulation stroke in adults. 3. To study the risk factor prevalence difference in gender among posterior circulation stroke and anterior circulation stroke in adults. 4. To study risk factor profile difference between anterior and posterior circulation stroke in adults. MATERIALS AND METHODS: The study includes patients admitted in neuromedicine and medical wards and referral cases to Neurology out-patients in Government Rajaji Hospital, Madurai. Patient diagnosed to have ischemic stroke in adults more than 40 years are included in this study. This is a prospective study. METHODOLOGY: In this study, data will be obtained from patients who are diagnosed with stroke and are followed up in stroke clinics. Patients can only participate in this study after signing and dating the inform consent. Patient’s demographic characteristics, stroke risk factors profiles, stroke frequencies, and Information of neuroimaging features and their relationships with strokes are also obtained. Inclusion criteria: (Based on National Institute of Health criteria) • Age greater than 40 years. • Agreed to participate in the study and sign the consent form. • Hypertension > 140/90 mm Hg. • Fasting blood sugar more than 140 mg/dl in atleast 2 occasions. • Total cholesterol more than 240 mg/dl. • LDL cholesterol more than 130 mg/dl. Exclusion criteria: • Patient's refusal to participate in the study. • Patients with haematological malignancies and bleeding diasthesis. • Patients with cardiac disease and atrial fibrillation. CONCLUSION: 1. 120 cases of each stroke subtypes were studied and their stroke risk factor profiles were assessed. 2. Stroke risk factor profile of both anterior circulation stroke and posterior circulation stroke were compared and analysed statistically. 3. Study showed in anterior circulation stroke, the age of stroke occurrence was earlier than posterior circulation stroke and was statistically significant. 4. Study showed stroke was more prevalent in females than males in both stroke subtypes. 5. On comparing the risk factor- diabetes, between anterior and posterior circulation stroke, there was statistically non-significant difference in prevalence of this risk factor between these groups. 6. Considering the prevalence of hyperlipidemia among both stroke sub groups, there was no significant difference statistically. 7. The study showed both hypertension and smoking, the major stroke risk factor had higher occurrence among posterior circulation stroke group than other stroke subgroup. 8. As Posterior circulation stroke are more severe in nature, control of both these more prevalent risk factor like hypertension and smoking helps to reduce the mortality of stroke.

Item Type: Thesis (Masters)
Additional Information: Reg.No.16101101
Uncontrolled Keywords: Risk Factors, Anterior and Posterior Circulation Stroke, Adults.
Subjects: MEDICAL > Neurology
Depositing User: Subramani R
Date Deposited: 27 Mar 2020 09:55
Last Modified: 27 Mar 2020 09:55
URI: http://repository-tnmgrmu.ac.in/id/eprint/12493

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