Aparna, M P (2014) A Prospective study to compare T2 Weighted MRI to CT imaging in volume delineation for radiotherapy planning in carcinoma cervix. Masters thesis, Christian Medical College, Vellore.
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Abstract
OBJECTIVES: To compare magnetic resonance imaging (MRI), computed tomography (CT), and clinical examination to evaluate the impact of MRI on target volume delineation as compared to the volumes obtained on a CT scan and also to see the effect on staging and prognosis. METHODS: Twenty patients diagnosed with locally advanced carcinoma cervix underwent planning CT abdomen and pelvis which was fused with T2 weighted MRI images to evaluate the impact of MRI on target volume delineaton , to see if CT scan along with clinical findings can be a good alternate to MRI scan.A descriptive analysis and frequency distribution of the patient characteristics was done. Fisher's exact test was done to find out relationship between prognostic factors and image findings. PABAK was done to compare different imaging modalities (CT versus MRI).Paired T test was used for tumor volume comparison. RESULTS: MRI was better in tumor delineation as compared to CT scan. Additional imaging gave information regarding local extent of the disease, nodal involvement . Upstaging of disease helped in selecting appropriate treatment modality. CONCLUSION: Though the findings on CT, MRI, or PET examinations are not mandatory for FIGO staging it could be of additional benefit and provide extra information that would result in stage migration, help appropriate selection of treatment modality,result in more accurate radiotherapy treatment planning and also provide prognostic information that would impact on the outcome of treatment and survival. CT with good clinical examination could be used as an alternate to MRI where MRI is not feasible.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | MRI, CT, carcinoma cervix, staging and Radiotherapy planning. |
| Subjects: | MEDICAL > Radio Therapy |
| Depositing User: | Subramani R |
| Date Deposited: | 23 Mar 2020 15:34 |
| Last Modified: | 23 Mar 2020 15:34 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/12420 |
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