Study of risk of malignancy index scoring system in the preoperative evaluation of patients with ovarian tumor and its correlation with histopathological examination

Mythily, M (2017) Study of risk of malignancy index scoring system in the preoperative evaluation of patients with ovarian tumor and its correlation with histopathological examination. Masters thesis, Stanley Medical College, Chennai.

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Abstract

BACKGROUND: The discrimination between benign and malignant ovarian tumor is important in considering an optimal plan for an appropriate surgical treatment. OBJECTIVE: To evaluate the ability of risk of malignancy index based on menopausal status, ultrasonographic score and serum level of CA125 to discriminate between benign and malignant ovarian tumor. MATERIAL AND METHODS: This is a prospective observational study of 100 patients of all age group who admitted with a diagnosis of ovarian tumor at Govt. R.S.R.M Lying in hospital, Chennai during the period of 2015 to 2016 . The sensitivity, specificity, positive predictive value and negative predictive value of different cut off values of RMI were calculated. Finally it was correlated with histopathological examination. RESULTS: By comparing the RMI with different cut off values, the RMI with cut off value 200 gave sensitivity 82.6%, specificity 94.8%, positive predictive value 82.6% and negative predictive value 94.8%. It was significantly better in predicting malignancy. CONCLUSION: The RMI is able to discriminate between benign and malignant ovarian tumors. The RMI with a cut off value 200 was the most reliable in predicting malignancy. It is a simple method that can be incorporated into clinical practice easily to enable the selection of patients for proper referral to tertiary care centre.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Risk of malignancy index, Serum CA125, Menopausal status, Ultrasonographic score, Ovarian tumor.
Subjects: MEDICAL > Obstetrics and Gynaecology
Depositing User: Devi S
Date Deposited: 20 Mar 2020 03:12
Last Modified: 20 Mar 2020 03:12
URI: http://repository-tnmgrmu.ac.in/id/eprint/12383

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