Jayanandhini, M (2016) Study of Expression of cd117 in Glial Tumors and its role in Tumour Type and Grade. Masters thesis, Madras Medical College, Chennai.
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Abstract
Glial tumors are a varied group of neoplasm. CD117 is a protooncogene encoded tyrosine kinase receptor. It is expressed usually in some normal tissues and in neoplasms like GIST.(gastrointestinal stromal tumors) . Treatment with inhibitors of receptor for tyrosine kinase namely imatinib is proved successful in cases like gastrointestinal stromal tumour which are CD117- positive. Likewise aim of this study is to evaluate the expression of CD117 in tumors of glial origin,to prove the marker as useful marker for diagnostic purpose and also therapeutic purpose. This study also includes analysis of CD117 expression in glial tumor subtypes and grades.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | CD117 ; gliomas ; high grade tumours ; GIST ; imatinib. |
| Subjects: | MEDICAL > Pathology |
| Depositing User: | Laksham S |
| Date Deposited: | 07 Jul 2017 09:59 |
| Last Modified: | 08 Nov 2018 07:43 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/1232 |
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