Comparison of Efficacy of Negative Pressure Wound Therapy Vs Conventional Normal Saline Dressing in Diabetic Foot

Raja Chandrasekar, M (2017) Comparison of Efficacy of Negative Pressure Wound Therapy Vs Conventional Normal Saline Dressing in Diabetic Foot. Masters thesis, Stanley Medical College, Chennai.

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Abstract

This study was conducted in forty patients who came with diabetic foot ulcers where NPWT and conventional normal saline dressing was applied. After randomizing patients into two groups of twenty patients each, group A received NPWT and the group B received conventional normal saline dressings. The study outcome was studied was assessed in terms of reduction in duration of wound closure, reduction of bacteriological burden of diabetic wounds. Age, gender distribution, types of wounds, pus culture negativity, duration of wound closure were all comparable between the two groups. 13 wounds became pus culture negative for organisms in 3rd culture sample in NPWT group, but in conventional group, only 9 patients attained pus culture negativity in 8th sample. And this showed the power of NPWT in reducing the bacteriological burden of diabetic wounds. 11 out of 20 patients, wound closure was attained within or equal to 2 weeks in NPWT group.8 out of 20 patients, wound closure was attained within or equal to 4 weeks. And this showed the power of NPWT in reducing the duration of wound closure mainly by skin grafting. Complete clearance of aerobic flora and anerobic flora was observed much earlier in patients who received NPWT. CONCLUSION: NPWT was effective in reduction in reduction of bacterial flora of diabetic wounds as the wound showed pus culture & sensitivity negative for growth. NPWT was effective in clearing aerobes and anerobic bacteria well. Very effective in clearing pseudomonas which was the most common organism isolated from the wound. NPWT although it created an anerobic atmosphere around the wound, did not induce proliferation of anerobes. NPWT caused an increase in proliferation of granulation tissue which was essential for wound closure especially by skin grafting. Hence we found that NPWT Was effective in reducing the bacterial burden of the wound and caused proliferation of granulation tissue needed for wound closure and decreased the duration of wound closure and hospital stay.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Comparison, Efficacy, Negative Pressure Wound Therapy, Conventional Normal Saline Dressing, Diabetic Foot.
Subjects: MEDICAL > General Surgery
Depositing User: Devi S
Date Deposited: 18 Mar 2020 03:25
Last Modified: 18 Mar 2020 09:07
URI: http://repository-tnmgrmu.ac.in/id/eprint/12317

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