Analysis of 100 Cases of Perforative Peritonitis: Studying the Prognostic Factors

Luqman Ahammed, P (2011) Analysis of 100 Cases of Perforative Peritonitis: Studying the Prognostic Factors. Masters thesis, Madurai Medical College, Madurai.


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INTRODUCTION: Perforative peritonitis is a common emergency encounnted by surgeons all over the world. It needs prompt diagnosis and equally rapid measures to correct the underlying derangement. The etiology of perforative peritonitis is varied and diverse, varying with the geographical location, culture characteristics and age of the patient among other factors. The spectrum of etiology of perforative peritonitis in tropical countries like India differ from its Western counter part, where lower Gastro intestinal perforation is common. Duodenal ulcer perforation is the commonest type among Nontraumatic gastro-intestinal perforation. While the mortality of duodenal ulcer perforation has steadily declined all over the world in the last few decades it still remains a significantly mortal disease especially in developing countries. While with the advent of better antibiotics enteric fever is easily curable, its complications like enteric perforation do occur from time to time primarily because of the failure to recongise therapy. AIM OF STUDY: The aim of my study is to study the prognosis of various perforative peritonitis on the basis of 1. Age of the patient, 2. Site of perforation, 3. Size of perforation, 4. Time of presentation. MATERIAL AND METHODS: This is a prospective study has been based on the analysis of 100 cases of perforative peritonitis admitted under the department of General Surgery, Government Rajaji Hospital, Madurai from October 2008 to October 2011. Cases were admitted as emergency and possible immediate investigations were done. Exclusion Criteria: 1. Traumatic perforations were excluded, 2. Appendicular mass excluded. Statistical Tools: The information collected regarding all the selected cases were recorded in a Master Chart. Data analysis was done with the help of computer using Epidemiological Information Package (EPI 2008) developed by Centre for Disease Control, Atlanta. Using this software range, frequencies, percentages, means, standard deviations, chi square and 'p' values were calculated. Kruskul Wallis chi-square test was used to test the significance of difference between quantitative variables. A 'p' value less than 0.05 is taken to adenote significant relationship. CONCLUSION: 1. In non-Traumatic gastro – intestinal perforation duodenal ulcer perforation is the commonest (61). 2. Males are more commonly affected than females (8.09:1). 3. The incidence on Non-traumatic gastro – intestinal perforation is high in the third and fourth decades of life. 4. Higher mortality and seen in elderly patients with perforative pertitonsis. 5. Outcome for colonic perforation is poor. 6. Patients managed conservatively has poor outcome. 7. Mortality is higher in Ileal perforation as compaired to Duodinal perforation. 8. Compared to other perforative peritonitis appedndicular perforation has a better outcome. 9. Complications are higher for ileal perforation, followed by appendicular and duodenal perforation.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Perforative Peritonitis, Analysis of 100 Cases, Prognostic Factors.
Subjects: MEDICAL > General Surgery
Depositing User: Devi S
Date Deposited: 18 Mar 2020 02:44
Last Modified: 18 Mar 2020 13:06

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