Prevalence of gastroesophageal reflux disease in patient with voice disorders

Maldhure Swati Vijay, (2011) Prevalence of gastroesophageal reflux disease in patient with voice disorders. Masters thesis, Christian Medical College, Vellore.


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INTRODUCTION: Acid reflux is a common problem in 4-10% of patients coming to ENT out patient departments. A recent study of voice and reflux disorders revealed that 55% - 60% patients had laryngopharyngeal reflux.1 Anti-reflux therapy is usually used as an empirical treatment for patients with hoarseness, where no other cause has been identified by examination. Gastro-esophageal reflux disease (often abbreviated to GERD or GORD) is defined as the retrograde flow of gastric contents into the oesophagus or above. Gastro-esophageal reflux disease is characterized by symptoms and/or signs of mucosal injury of the oesophagus or upper aerodigestive tract secondary to this reflux. AIM OF THE STUDY: To determine the prevalence of gastro-esophageal reflux disease in patients with voice disorders. OBJECTIVES: 1. To determine the prevalence of gastro esophageal reflux disease (GERD) in patients with voice disorders. 2. To determine prevalence of laryngopharyngeal reflux (LPR) in patients with gastro-esophageal reflux disease by validating the following, in patients with gastro-esophageal disease: Kaufmann Reflux Symptom Index, Reflux Finding Score MATERIAL AND METHODS: Study Design: This was a prospective, descriptive cross sectional study. Subjects: The study patients were those who attended the ENT Out Patient Clinics of Christian Medical College & Hospital with history of change in voice for more than three weeks. Inclusion criteria: More than 18 years of age, Any gender. Exclusion Criteria: Laryngeal papillomatosis, Carcinoma larynx, Vocal cord palsy, Hypothyroidism, Neurological deficits causing change in voice, Have received proton pump inhibitors, Received H2 receptor antagonists, Receiving calcium channel blockers, Receiving anti dopminergic drugs like domperidone, Receiving α and β blockers, Allergic to any anesthetic agent, Chronic pulmonary disease, asthma, Heart disease, Scleroderma, Pregnancy. CONCLUSION: 1. The prevalence of gastro-esophageal reflux disease (GERD) in our patients with voice disorder was 36.7%. 2. There was no significant statistical co-relation between Koufman Reflux Symptom Index, Laryngopharyngeal reflux and GERD. 3. There appears to be some co-relation between Reflux Finding Score, Laryngopharyngeal reflux and GERD (p value- 0.063). Further evaluation including increase in the sample size may provide significant results. 4. Unlike other studies, GERD in voice disorder patients was predominant in males in our study. 5. Voice disorder in level II voice user was due to voice overuse and in level III & IV voice user were probably due to GERD. 6. There was no statistical co-relation between GERD, voice disorder, smoking and alcohol in our study.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Prevalence, gastroesophageal reflux disease, voice disorders.
Subjects: MEDICAL > Otolaryngology
Depositing User: Devi S
Date Deposited: 16 Mar 2020 01:33
Last Modified: 16 Mar 2020 11:39

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