OPC Poisoning and Serum Cholinesterase Levels

Owaise Ahmed, M (2017) OPC Poisoning and Serum Cholinesterase Levels. Masters thesis, Stanley Medical College, Chennai.


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OP Poisoning is a major public health problem in the developing world. Clinical manifestations following OP poisoning can be associated with the extent of decrease of Pche. This study was undertaken to find out the relationship between OPC poisoning and serum cholinesterase levels. Cholinesterase is an enzyme which is responsible for breakdown of Acetyl Choline. OPC compounds being anticholinesterases increases acetyl choline level in the synaptic cleft thereby producing clinical toxicity. All patients admitted with OPC poisoning are given Atropine and Pralidoxime. However it was found in various studies that serum cholinesterase level does not correlate with total dose of Atropine and hence has no prognostic value in various organophosphorus poisoning.

Item Type: Thesis (Masters)
Uncontrolled Keywords: OPC Poisoning, Serum Cholinesterase Levels.
Subjects: MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 12 Mar 2020 10:53
Last Modified: 12 Mar 2020 10:53
URI: http://repository-tnmgrmu.ac.in/id/eprint/12226

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