Study of bacteriology in cholesteatoma cases.

Arumugam, K (2008) Study of bacteriology in cholesteatoma cases. Masters thesis, Madurai Medical College, Madurai.


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As per the statistics one out of five patients attending a general hospital complaints of so for problems in his /her Ear, Nose, Throat or head and neck. As the incidence of chronic suppurative otitis media depend on socio economic factor over crowding, poor hygiene and poor nutrition so the disease is wide spread in India. Chronic suppurative otitis media is the most common clinical entity in otorhinolaryngology clinic especially in our part of the world. Culture of aural swab and cholesteatoma matrix demonstrates the polymicrobial bacteriology consisting of both gram positive and gram negative pathogens. Gram negative pathogen form the majority of aural swab and cholesteatoma matrix but the percentage is more in cholesteatoma matrix cultures. Mixed growth is more common in culture of aural swab the cholesteatoma matrix cultures probably due to contaminant of infection from external auditary canal, ascending infection via Eustachian tube and indiscriminate use of antibiotics. The antibiotic sensitivity study shows emerging resistant strain for the commonly used antibiotics including gentamycin which formed the drug of choice of earlier studies. It is probably due to the indiscriminate use of antibiotics. Even though the treatment for cholesteatoma is primarily surgical, because the elimination of pathogens depend upon the eradication of cholesteatoma, the knowledge of pathogens and their sensitivity will help in choosing the appropriate antibiotics during the post operative period which will prevent the development of resistant strain and complications.

Item Type: Thesis (Masters)
Uncontrolled Keywords: cholesteatoma; bacteriology
Subjects: MEDICAL > Otolaryngology
Depositing User: Devi S
Date Deposited: 06 Jul 2017 11:33
Last Modified: 31 Mar 2018 07:39

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