A Study on Category II Antituberculosis treatment under the Revised National Tuberculosis Control Programme covered by Christian Medical College, Vellore.

Prashanth, H R (2007) A Study on Category II Antituberculosis treatment under the Revised National Tuberculosis Control Programme covered by Christian Medical College, Vellore. Masters thesis, Christian Medical College, Vellore.


Download (216kB) | Preview


INTRODUCTION: Tuberculosis (TB) is a disease that has severely affected communities and Nations since times immemorial. The disease has brought untold miseries to Generations and even today, when newer modalities for diagnosis and treatment Of TB have made the disease curable, people are suffering and dying from the Disease. Tuberculosis remains the number one killer infectious disease affecting adults in Developing countries. The 1990 World Health Organization (WHO) report on the Global Burden of Disease ranked TB as the seventh most morbidity-causing Disease in the world, and expected it to continue in the same position up to 2020. During 2004, it was estimated that about nine million new cases of TB occurred Globally. India contributes a fifth of these cases, i.e., about 1.8 million, of which 0.8 million are new sputum-positive infectious cases. Nearly 400,000 estimated Deaths occur annually due to tuberculosis. 75% of the people with tuberculosis Are in the economically productive age group. BACKGROUND : Tuberculosis remains a major public health problem in India. From January 2001 onwards, the externally funded Revised National Tuberculosis Control Programme (RNTCP) with its DOTS strategy officially began in Vellore district of Tamil Nadu. Community health and development (CHAD) hospital run by the department of Community Medicine, Christian Medical College and Hospital (CMCH) Vellore, is functioning as a tuberculosis unit (TU) under the RNTCP. Vellore town patients are covered by the TB unit under Vellore District tuberculosis centre. There is an DOTS Clinic functioning in CMC hospital getting patients from all the departments of CMC. Annually around 600 patients will be started on Antitubercular Treatment (ATT) through the DOTS clinics and peripheral health systems. Cat II treatment constitutes about 10 – 15% of these cases. One of the challenges in tuberculosis is treating patients who have failed initial attempts to cure their disease. These patients are moved into Category II in an attempt to provide further intervention. OBJECTIVES : 1) To study the profile of tuberculosis patients on Category II Treatment in a population covered by CHAD/ C M C H DOTS clinic under RNTCP . 2) To study outcome of treatment in the same patients after a time of followup as compared to the immediate outcome after treatment. 3) To study the risk factors associated with poor outcomes in the above group of patients. CONCLUSIONS : Category II treatment under DOTS therapy still works with a success rate of 91.2% in patients who take prescribed duration of treatment as contrary to the belief that adding a single drug to a failing regimen will not help. • Inadequate Food and HIV co-infection play a major role in poor outcomes • Overall survival is better in treatment success patients.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Category Antituberculosis Treatment Under ; Revised National Tuberculosis ; Control Programme Covered ; Christian Medical College Vellore.
Subjects: MEDICAL > Community Medicine
Depositing User: Subramani R
Date Deposited: 12 Jul 2017 06:04
Last Modified: 12 Jul 2017 06:04
URI: http://repository-tnmgrmu.ac.in/id/eprint/1193

Actions (login required)

View Item View Item