Jayaraman, R (2012) A study on diagnostic significance of nerve conduction studies in early detection of Pure Neuritic Hansen’s disease. Masters thesis, Madras Medical College, Chennai.
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Abstract
INTRODUCTION: Hansen's disease is diagnosed by presence of skin lesions. However, in case of pure neuritic hansen's the diagnosis is delayed because of absence of skin lesions. The delay in diagnosis leads to delay in treatment which leads to formation of deformities. This study is aim that whether nerve conduction studies are helpful in subjecting the patient to early nerve biopsy. AIM OF THE STUDY: To study the diagnostic significance of nerve conduction studies in early detection of pure neuritic hansen's disease. MATERIALS AND METHODS: This study is a descriptive study of analysing the patients with clinical suspicion of pure neuritic Hansen's electro physiologically and later corrlating with the nerve biopsy results. 70 patients attending neurology OPD with clinical suspicion of pure neuritic hansen's disease were selected. Patients were evaluated for other diseases which can mimic Hansen's disease. Patients were subjected to sural nerve biopsy and then the findings were correlated with electro physiology. RESULTS: 16 out of 70 patients were diagnosed to have Hansen's disease by biopsy. The most common mimickers for Hansen's were Diabetic Neuropathy, HMSN and connective tissue disorders. Nerve conduction studies including sympathetic skin response were abnormal in all patients with Hansen's disease. It was also abnormal in other diseases like Diabetic Neuropathy and connective tissue disorders. CONCLUSION: All the patients with biopsy proven Hansen's disease showed abnormal nerve conduction studies. Since nerve conduction studies were also abnormal in other diseases it is not specific for Hansen's and based on that alone we cannot subject the patients for nerve biopsy. Nerve biopsy clinches the diagnosis.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | diagnostic significance, nerve conduction studies, early detection, Pure Neuritic Hansen’s disease. |
| Subjects: | MEDICAL > Neurology |
| Depositing User: | Subramani R |
| Date Deposited: | 11 Feb 2020 00:42 |
| Last Modified: | 11 Feb 2020 00:42 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/11897 |
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