A Prospective Open Labelled Phase-II Non Randomized Clinical Study of Nelli Kudineer for Rathamoolam (Bleeding Hemorrhoids)

Sumayya, M (2019) A Prospective Open Labelled Phase-II Non Randomized Clinical Study of Nelli Kudineer for Rathamoolam (Bleeding Hemorrhoids). Masters thesis, Government Siddha Medical College, Palayamkottai.


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The first known mention of the disease Rathamoolam (bleeding Hemorrhoids) is from 1700 BC Egyptian papyrus. The nature, etiology, types, clinical features and prognosis of Rathamoolam has mentioned in Yugimuni’s literature. The prevalence of Hemorrhoids ranges from 4.4% in the general population to 36.4% in general practice. Prevalence of Hemorrhoids in India according to recent survey is about 40 million. It is now considered a major cause of morbidity and imposes burden on the society both economically and socially. Males and Females are affected with about equal frequency. Siddha recommended the Compatible diet and activities, cost effective easily available preparations and management of Rathamoolam (RM). Nelli Kudineer (NK) is one of the effective Siddha herbal preparations, mentioned in Gunapadam Moolikai. 40 patients including OP & IP, both genders were selected according to the criteria mentioned in the proforma and they were administered with trial drug Nelli Kudineer 100ml in the morning before food for one month. The pre clinical and clinical evaluations of Nelli Kudineer were carried out and results were showed its effectiveness for Rathamoolam. The panchabootham and its relations with gunam of Nelli Kudineer were proven for their activity in relieving the symptoms of Rathamoolam. The gradation of result was found to be good improvement in 73% cases, moderate improvement in 23% cases and mild improvement in 4% cases.

Item Type: Thesis (Masters)
Additional Information: (Reg.No.321611010)
Uncontrolled Keywords: Nelli Kudineer, Rathamoolam, Bleeding Hemorrhoids, Prospective Open Labelled Phase-II Non Randomized Clinical Study.
Subjects: AYUSH > Maruthuvam
Depositing User: Subramani R
Date Deposited: 02 Mar 2020 01:04
Last Modified: 03 Mar 2020 04:06
URI: http://repository-tnmgrmu.ac.in/id/eprint/11896

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