A study on clinical profile of seizures: Current clinical scenario

Namitha, Narayanan (2011) A study on clinical profile of seizures: Current clinical scenario. Masters thesis, Stanley Medical College, Chennai.

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Abstract

AIM OF THE STUDY: To study the profile of the patients with seizures attending Stanley Medical College Hospital with relevance to age group, type of seizure, sex predilection, etiology with EEG and CT/MRI correlation. To determine the prevalence of various type of seizures as in our hospital setup. MATERIALS AND METHODS: 200 patients who attended department of Medicine/ Neuromedicine, Govt. Stanley Hospital with history of seizures from October 2009 to October 2010. All patients in the age group > 12 yrs presenting with history of seizures were included in the study. Patients with the below mentioned features were excluded from the study. Critically ill patients with acute Metabolic derangements, Patients admitted with history of Poisoning, Patients admitted with history of Attempted Hanging, Patients with Hepatic Failure, Patients with Renal Failure. A detailed history of Presenting Illness, Past history, Family, Personal and Social history were obtained along with occupation and socio economic status from the patient and reliable attendees. Details of the seizures included: First attack, Last attack, Type of seizures, Part of body involved, Duration, Frequency, Maximum period of freedom. Time of attack, Precipitating factors, Aura, Post-ictal symptoms, automatism. CONCLUSION: Generalised seizures (70.5%) were more common than partial seizures (29.5%). GTCS was the commonest seizure type (68.5%). Among the partial seizures, partial seizures with secondary generalization (15.5%) was most common. Males ( 59.5%) were more in number than females in patients presenting with seizures. Patients aged more than 40 years constituted a significant proportion (33.5%) of patients presenting with seizure disorder. An organic cause for seizures could be identified in most of those patients. A secondary rise in incidence of new onset seizures occurred in patients aged more than 40 years. Imaging was normal in 64.5% of cases and abnormal in remaining cases. Neuroimaging was abnormal in 71% of patients who presented with partial seizures. Hence imaging plays a crucial role in the management of patients presenting with partial seizures. Abnormal EEG tracings were found only in 39% of patients presented with seizures in this study. 44% of cases with partial seizures had EEG abnormalities as against 37% in patients with generalised seizures. In most of the patients EEG was done at a later date after the seizures were well controlled. Studies indicate that a higher yield of abnormalities and more precise definition of seizure type can be obtained during the ictal or in the immediate post-ictal state. In 38.5% of the cases who presented with seizures both neuroimaging and EEG studies were normal.

Item Type: Thesis (Masters)
Uncontrolled Keywords: seizures, clinical profile, Current clinical scenario.
Subjects: MEDICAL > General Medicine
Depositing User: Devi S
Date Deposited: 13 Jan 2020 05:03
Last Modified: 13 Jan 2020 12:00
URI: http://repository-tnmgrmu.ac.in/id/eprint/11814

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