Susan George, (2019) Study on Etiological Profile of New Onset Seizures in Adults in Tertiary Care Centre. Masters thesis, Tirunelveli Medical College, Tirunelveli.
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Abstract
BACKGROUND: Seizures are one of the commonest neurological disorders we encounter in our daily medical practice. Myriad are the causes that can precipitate a seizure. These causes vary between countries and states depending on the demographic features and genetics of the resident population. AIM OF THE STUDY: To know about various causes of new onset seizures in adults and to find out the commonest cause in various age groups in this part of south Tamilnadu. MATERIALS & METHODS: 206 cases of new onset seizures admitted during period of March 2017 to March 2018 were included for this prospective observational study. Information were gathered using a prepared proforma. RESULTS: New onset seizures had a male predominance with male : female ratio of 1.2:1. First episode of seizures were most common in 21-30 years with incidence of 24%. Overall most common seizure type was generalised tonic clonic seizures, with incidence 71%. Most common aetiology was cerebrovascular accidents (27%) followed by CNS infections (23%). Among cerebrovascular accidents most common was ischemic stroke (50%) while TB meningitis attributed to maximum cases among infections (38%). Cerebral venous thrombosis accounted for highest number of cases among cerebrovascular accidents in younger age group with a male to female ratio 3:1. Familial adult onset myoclonic epilepsy accounted for 5%, not mentioned as a cause for new onset seizures in similar studies and was unique to a community in this part of south Tamilnadu. CONCLUSION: After the study various etiologies causing new onset seizure were found out. Also commonest etiology in various age groups were identified.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | New onset seizures, familial adult onset myoclonic epilepsy. |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 25 Aug 2019 03:50 |
| Last Modified: | 25 Aug 2019 03:56 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/11200 |
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