Study on Etiological Profile of New Onset Seizures in Adults in Tertiary Care Centre

Susan George, (2019) Study on Etiological Profile of New Onset Seizures in Adults in Tertiary Care Centre. Masters thesis, Tirunelveli Medical College, Tirunelveli.


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BACKGROUND: Seizures are one of the commonest neurological disorders we encounter in our daily medical practice. Myriad are the causes that can precipitate a seizure. These causes vary between countries and states depending on the demographic features and genetics of the resident population. AIM OF THE STUDY: To know about various causes of new onset seizures in adults and to find out the commonest cause in various age groups in this part of south Tamilnadu. MATERIALS & METHODS: 206 cases of new onset seizures admitted during period of March 2017 to March 2018 were included for this prospective observational study. Information were gathered using a prepared proforma. RESULTS: New onset seizures had a male predominance with male : female ratio of 1.2:1. First episode of seizures were most common in 21-30 years with incidence of 24%. Overall most common seizure type was generalised tonic clonic seizures, with incidence 71%. Most common aetiology was cerebrovascular accidents (27%) followed by CNS infections (23%). Among cerebrovascular accidents most common was ischemic stroke (50%) while TB meningitis attributed to maximum cases among infections (38%). Cerebral venous thrombosis accounted for highest number of cases among cerebrovascular accidents in younger age group with a male to female ratio 3:1. Familial adult onset myoclonic epilepsy accounted for 5%, not mentioned as a cause for new onset seizures in similar studies and was unique to a community in this part of south Tamilnadu. CONCLUSION: After the study various etiologies causing new onset seizure were found out. Also commonest etiology in various age groups were identified.

Item Type: Thesis (Masters)
Uncontrolled Keywords: New onset seizures, familial adult onset myoclonic epilepsy.
Subjects: MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 25 Aug 2019 03:50
Last Modified: 25 Aug 2019 03:56

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