A Study of the Placental Changes in High Risk Pregnancy

Almas Banu, M (2019) A Study of the Placental Changes in High Risk Pregnancy. Masters thesis, Tirunelveli Medical College, Tirunelveli.

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Abstract

AIMS AND OBJECTIVES: To observe and study the various gross morphological and histopathological changes that occurs in placentas of high risk mothers in TVMCH, Tirunelveli. MATERIAL AND METHODS: 98 placentas which were obtained from high risk pregnancies were studied. The placentas were collected 10 % neutral buffered formalin. The tissue were processed and stained. The gross morphological changes and histopathological changes were noted. RESULTS: Out of 16 placentas studied from hypertensive disorders of pregnancy, 62.5% show infarction, 75% show perivillous fibrinoid. Out of 15 placentas of anaemia studied, 53% showed perivillous fibrionoid, 20% showed increased vascularity of villi. Out of 13 placentas of intrauterine death studied 38% show fibrinoid necrosis, 69% show perivillous fibrinoid, 62% show intervillous haemorrhage, 38% show smooth muscle proliferation. Out of 11 placentas of oligohydramnios, 45% showed smooth muscle proliferation. Out of 13 cases of placenta creta studied, 8 placentas had the predisposing factor of placenta previa. CONCLUSION: This study throws light on the morphological and histological changes of placenta in high risk pregnancies. This helps us to understand the etio-pathogenesis of high risk pregnancy.

Item Type: Thesis (Masters)
Uncontrolled Keywords: High risk pregnancy, perivillous fibrinoid, increased villous vascularity, intra uterine death, hypertensive disorders of pregnancy, fibrinoid necrosis.
Subjects: MEDICAL > Pathology
Depositing User: Subramani R
Date Deposited: 23 Aug 2019 15:25
Last Modified: 24 Aug 2019 08:19
URI: http://repository-tnmgrmu.ac.in/id/eprint/11159

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