Farhan Adam Mukadam, (2019) Comparison of Intra-Arterial Pressures in Fluid-filled Catheter-Transducer Systems with Different Catheter-tip Configurations: Standard v. Modified. Masters thesis, Christian Medical College, Vellore.
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Abstract
BACKGROUND: A key parameter monitored in any critical care unit, for the hemodynamic stability of the patient, is the intra-arterial blood pressure. Despite the clear advantage of having real-time streaming data of this vital parameter, most practitioners are unaware of how erroneous this can be with the use of the current standard; the fluid-filled catheter-transducer system. OBJECTIVES: To design a physical simulation that tests catheter-transducer systems and characterize the dynamic response of such systems. To modify the catheter-tip and compare its performance against a gold standard. METHODS: A carefully designed catheter-tranducer testing system was constructed covering the full range of physiological limits. Dynamic response of each configuration was tested and the most appropriate identified. Code was written to automate peak detection and calculation of the dynamic response parameters. Catheter-tip modifications were tested against the gold standard of a solid-state microtransducer, in different settings of the simulation. Data was acquired in PowerLab and analysis algorithms implemented in MATLAB R2018a. RESULT: The experimental setup designed proved consistent and covered the full range of physiological limits. The algorithms to evaluate dynamic response showed repeatable performance for any flush test conducted. The modification of the tip showed no improvement over the standard tip for any parameter. CONCLUSION: The modular nature of the testing system designed, affords the ability to simulate various scenarios of pressure recording, such as vasospasm, peripheral vasoconstriction and vasodilation. The pitfalls in the catheter-transducer system should be kept in mind while recording and steps should be taken to minimize them. Documentation of the dynamic response of the system is essential to prove the fidelity of the recording.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | Reg.No.201615353 |
| Uncontrolled Keywords: | intra-arterial blood pressure, dynamic response. |
| Subjects: | MEDICAL > Physiology |
| Depositing User: | Subramani R |
| Date Deposited: | 23 Aug 2019 02:06 |
| Last Modified: | 23 Aug 2019 02:06 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/11110 |
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