Suganya, C (2019) Investigate the Prevalence and Association of Metabolic Syndrome and Its Components in Patients with OSA and Without OSA: A Hospital Based Cross Sectional Study. Masters thesis, Madras Medical College, Chennai.
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Abstract
INTRODUCTION: The combination of obstructive sleep apnea and metabolic syndrome has been termed as syndrome z. Sleep related breathing disorders and metabolic syndrome are on increasing trend because of epidemic of obesity. Beyond their epidemiologic relationship, growing evidence suggests that OSA may be causally related to metabolic syndrome. AIMS AND OBJECTIVES: To estimate the prevalence of metabolic syndrome in patients with OSA To estimate the association of metabolic syndrome and its components in patients with and without OSA. MATERIALS AND METHODS: Hospital based prospective cross sectional analytical study. OBSERVATION: In this study prevalence of metabolic syndrome was 57.4 percent among OSA group in south Indian hospital based population and 34.7 percent in the patients without OSA. In our study prevalevalence of metabolic syndrome was higher in the patients with severe osa than mild and moderate osa. We compared various variables of the metabolic syndrome independently with obstructive sleep apneA. of the various variables of metabolic syndrome like fasting blood glucose, blood pressure, HDL cholesterol and abdominal circumference diastolic blood pressure and HDL cholesterol shows significant association with metabolic syndrome with p value of less than 0.005. CONCLUSION: The clinical implications are that there is a high prevalence of metabolic syndrome in patients presenting to sleep clinics with symptoms suggestive of Obstructive sleep apnea, irrespective of whether they have obstructive sleep apnea or not. The prevalence of MS is even higher if they have obstructive sleep apnea.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | OSA, Metabolic Syndrome, Fasting Blood Glucose, Blood Pressure, HDL Cholesterol and Abdominal Circumference. |
| Subjects: | MEDICAL > Tuberculosis and Respiratory Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 19 Aug 2019 01:02 |
| Last Modified: | 19 Aug 2019 01:02 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/10976 |
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