Neurocognition and Disability in Patients with Schizophrenia compared with Healthy Controls

Sheerin Fathima, A S (2019) Neurocognition and Disability in Patients with Schizophrenia compared with Healthy Controls. Masters thesis, PSG Institute of Medical Science and Research, Coimbatore.


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BACKGROUND: Majority of patients with schizophrenia have life-long disability in their social and occupational functioning. Cognitive impairment is recognized as an important domain of schizophrenia, with a wide range of deficits seen among patients with schizophrenia. AIM OF THE STUDY: The current study aimed at assessing the neurocognitive function in clinically stable schizophrenia patients, in comparison with age and gender matched controls. Secondary aim was to assess any correlation between neurocognitive deficits and duration of illness; neurocognitive deficits and disability among patients with schizophrenia. METHODOLOGY: 20 clinically stable schizophrenics & 20 age and gender matched healthy controls were included in the study. Select 8 tests from the NIMHANS Neuropsychological battery was used to assess the neurocognitive functions such as attention, processing speed, verbal learning and memory, executive functions, visual memory and visuospatial skills. RESULTS: Results revealed a statistically significant difference between the two groups in the performance of all neurocognitive tests, with the schizophrenia patients group scoring lesser. Within the patient group, those with duration of illness < 2 years scored more on tasks for attention, verbal learning and memory and visual memory & had lower degree of disability, which were statistically significant. CONCLUSION: The current study emphasizes on the importance of assessing neurocognitive functions in all schizophrenia patients. Recently, cognitive remediation therapy is being done to improve the neurocognitive functioning which can have a significant implication on the overall well-being of the patient.

Item Type: Thesis (Masters)
Uncontrolled Keywords: neurocognition, cognitive deficits, schizophrenia, disability, functional, neuropsychological.
Subjects: MEDICAL > Psychiatry
Depositing User: Subramani R
Date Deposited: 19 Aug 2019 01:01
Last Modified: 19 Aug 2019 01:01

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