Efficacy of Botulinum Toxin-A Versus Methyl Prednisolone Acetate Injection in Reducing Pain and Improving Functional Outcome in Plantar Fasciitis

Geetha, T (2019) Efficacy of Botulinum Toxin-A Versus Methyl Prednisolone Acetate Injection in Reducing Pain and Improving Functional Outcome in Plantar Fasciitis. Masters thesis, Madras Medical College, Chennai.

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Abstract

OBJECTIVE: The efficacy of Botulinum Toxin-A Versus Methyl Prednisolone Acetate injection in reducing pain and improving functional outcome in plantar fasciitis. STUDY DESIGN: A Randomized Controlled Study. SAMPLE SIZE: 100 participants with plantar fasciitis divided into two groups by simplified randomized controlled method. METHODS: Participants in group 1 received 50 units of Botulinum Toxin-A which is mixed with given normal saline and group 2 received 40mg Methyl Prednisolone Acetate around plantar fascia close to calcaneal tuberosity. Participants are followed up at 1 month, 2 month, 4 month and 6month after intervention. Plantar fascia thickness before and after intervention done at 6 months by using Ultrasonagram. OUTCOME MEASURES: Visual analogue pain scale (VAS) and Foot ankle ability measure score (FAAM) are done at follow up months. RESULTS: This study shows statistically significant changes in both groups in first 4 months but the Botulinum Toxin-A group shows better pain relief and functional improvement ( p value < 0.0001) and it is maintained at 6 months in comparison to Methyl prednisolone acetate group (p value < 0.001). No side effects are noted in Botulinum Toxin-A group. CONCLUSION: Botulinum Toxin-A injection is found to be cost effective in chronic plantar fasciitis and it yields significant pain relief and functional improvement and it is maintained at 6 months when compared with steroid where there is significant decline in functional improvement after 4 months.

Item Type: Thesis (Masters)
Additional Information: Reg.No.201729001
Uncontrolled Keywords: Plantar fasciitis, Botulinum Toxin-A, Ultrasonagram, Visual analogue pain scale, Foot ankle ability measure.
Subjects: MEDICAL > Physical Medicine and Rehabilitation
Depositing User: Subramani R
Date Deposited: 19 Aug 2019 01:01
Last Modified: 19 Aug 2019 01:01
URI: http://repository-tnmgrmu.ac.in/id/eprint/10956

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