Evaluation of Levels of Adiponectin and Resistin in Gingival Crevicular Fluid in Periodontal Health, Disease and After Treatment: A Clinico Biochemical Study

Fairlin, P (2019) Evaluation of Levels of Adiponectin and Resistin in Gingival Crevicular Fluid in Periodontal Health, Disease and After Treatment: A Clinico Biochemical Study. Masters thesis, J.K.K. Nattraja Dental College and Hospital, Komarapalayam.

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Abstract

INTRODUCTION: Chronic Periodontitis is an inflammatory disease of the supporting tissues of the teeth. Resistin is a proinflammatory cytokine which is seen elevated in inflammatory conditions. Adiponectin mediates anti-inflammatory effects and functions in cell proliferation, differentiation, and regeneration. GCF collection is considered the most nontraumatic investigational method about periodontal tissue conditions. AIMS & OBJECTIVES: This study was done to evaluate the levels of GCF resistin and adiponectin in generalized chronic periodontitis patients before and after non surgical periodontal therapy. MATERIALS AND METHODS: GCF samples were collected from a total of 50 subjects divided into three groups, group I- Healthy, group II- Chronic Periodontitis, group III- After treatment. The levels of resistin and adiponectin were evaluated using Immunotag™ Human RETN ELISA kit (ITEH0269) and Immunotag™ Human ADP (Adiponectin) ELISA kit (ITEH2593). RESULTS: There was an increase in the level of resistin and decrease in the level of adiponectin in the GCF samples collected baseline. After 21 days of post treatment there was a decrease in the level of resistin and increase in the level of adiponectin. CONCLUSION: Resistin and adiponectin can be used as a potential marker in generalized chronic periodontitis patients.

Item Type: Thesis (Masters)
Additional Information: Reg.No. 241613102
Uncontrolled Keywords: Chronic Periodontitis, Resistin, Adiponectin, Inflammatory cytokines, Gingival Crevicular Fluid.
Subjects: DENTAL > Periodontology
Depositing User: Subramani R
Date Deposited: 15 Aug 2019 03:08
Last Modified: 15 Aug 2019 03:08
URI: http://repository-tnmgrmu.ac.in/id/eprint/10884

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