Duraimurugan, S (2019) Liquid Nitrogen Cryotherapy in Management of Oral Lesions. Masters thesis, Adhiparasakthi Dental College and Hospital, Melmaruvathur.
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Abstract
AIM AND OBJECTIVES: Evaluation of the efficacy of cryotherapy as a treatment modality for Oral lesions. OBJECTIVES: To evaluate the post -operative clinical outcome of oral lesions after treatment with cryotherapy, with respect to • Post -operative wound healing. • Recurrence of the lesion. MATERIALS AND METHODS: STUDY DESIGN: SAMPLE SIZE: A sample size of 15 oral lesions. • Al l the subjects, selected on the basis of inclusion criteria were treated with cryogun spray cryotherapy, using liquid nitrogen. Clinical photographs of the lesions were taken prior to cryotherapy and the procedure is performed. SOURCE OF DATA: This study was undertaken up for the outpatient who reported to Adhiparasakthi Dental College & Hospital. Patients were included in the study were those affected with oral lesions, either benign or premalignant lesions. 15 patients who were randomly selected from the outpatient, to evaluate the effectiveness of cryosurgical method of treating or al lesions with liquid nitrogen after obtaining ethical clearance. METHOD OF COLLECTION OF DATA: This study was conducted in the Department of Oral and Maxillofacial surgery, Adhiparasakthi Dental College & Hospital with a sample size of 15 lesions. • In formed/written consent was taken from the subjects/care takers. • Routine, pre -surgical Haematologic investigations were done. INCLUSION CRITERIA: • Patients who diagnosed with benign or premalignant oral lesion. • Lesion size more than 1cm. • Patient willing for cryotherapy. • Patients under ASA I / ASA II category. EXCLUSION CRITERIA: • Patients diagnosed with oral malignant lesions. • Patients not willing for cryotherapy. • Medically compromised patients RESULTS The present study was conducted to evaluate the efficacy of cryotherapy as treatment modality for oral lesion, to evaluate the post operative clinical outcome of oral lesion after treatment with cryotherapy with respect to post-operative wound healing and recurrence of the lesion in the department of Oral and Maxillofacial Surgery, at Adhiparasakthi dental college and hospital. 15 patients who was affected with oral lesion either benign or pre-malignant lesion of size more than 1cm, were randomly selected from out-patient to evaluate the effectiveness of the cryosurgery method of treating oral lesion with liquid nitrogen after obtaining ethical clearance. The age of patients ranged between 22yrs -52yrs with 46.7% of male and 53.3% of female. The overall mean age of the study population 33.6. In this study the open method was used to treat the lesion by direct application of liquid nitrogen with cryogun spray, al l subjects selected on the basis of inclusion criteria. Among 15 patients, there were 5 mucocele lesions, 2 traumatic fibroma, 1 leukoplakia, 2 erythroplakia, 3 lichen planus, 2 Apthous ulcers were seen. The site of occurrence of the lesion varied in different subjects the lesions were present on the buccal mucosa, floor of the tongue, upper vestibule, lower vestibule. Post-treatment follow up was done at 3rd day, 1s t week and 1st month and 2nd. The results were evaluated statically with the help of Descriptive statistics and NPar tests: chi -square test, kolmogorov-smirnov test. CONCLUSION: Cryosurgery is the use liquid nitrogen were extreme cold is produced to destroy abnormal tissue. Cryosurgery is very safe, easy to perform and relatively inexpensive technique for treating various oral lesions in out-patient clinic it is very useful for oral lesion as the oral mucosa is humid which makes it an ideal site for freezing. With recent development of better equipment this mode of therapy appears to have a promising role in the management of benign mucosal lesion, more reasonable with adequate success, the procedure is relatively more acceptable and has shown to have, faster recovery. Though cryosurgery have some difficulties like portability of the cryogenic agent and storage of highly volatile material, it require special storage container for short - term storage and canister for dispensing the liquid from the container during its use, its advantages are numerous, this technique provide a bloodless field, less pain when compared to conventional surgery, anesthesia is optional, excel lent cosmetic results, low cost, low risk of infect ion, minimal wound care, no need of suture removal, no work or sports restrict ions, short preparation time, useful in pregnancy. In this study the open method used to treat lesion with cryogen spray using liquid nitrogen has shown significantly good results in achieving complete regression of the benign and premalignant lesion of oral cavity.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Liquid Nitrogen Cryotherapy ; Management ; Oral Lesions. |
| Subjects: | DENTAL > Oral and Maxillofacial Surgery |
| Depositing User: | Subramani R |
| Date Deposited: | 13 Aug 2019 01:15 |
| Last Modified: | 13 Aug 2019 01:15 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/10853 |
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