Impaired Glucose Tolerance in Acute ST Elevation Myocardial Infarction - A Perspective study.

Prathap Kumar, G (2006) Impaired Glucose Tolerance in Acute ST Elevation Myocardial Infarction - A Perspective study. Masters thesis, Madurai Medical College, Madurai.

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Abstract

INTRODUCTION : Acute Myocardial Infarction is a serious and life threatening disorder. There are various risk factors for the development of Acute Myocardial Infarction. Of them, the most important and the one which is causing havoc among South Asian and Indian population is the relationship between abnormal glucose metabolism and Acute Myocardial Infarction. It is a well known fact that Diabetes Mellitus, a full blown form of abnormal glucose metabolism is associated with increased risk of cardiovascular events like AMI, unstable angina, Cerebrovascular events like stroke & also with peripheral vascular disease. Whether the new concept of Impaired Glucose Tolerance, Impaired Fasting Glucose also have similar effects on the morbidity and mortality of the patients with AMI & their relationship is either causal or casual needs to be urgently evaluated. Also, the incidence of Impaired Glucose Tolerance, Impaired Fasting Glucose is increasing in the population especially among the Indians and South East Asians. The Impaired Glucose Tolerance, Impaired Fasting Glucose are considered as prediabetic state, in the contemporary literature. Whether the detection of an individual in this prediabetic state & proper treatment with life style modification can bring down the risk of future cardio vascular events like Unstable Angina, AMI are questions to be answered. AIMS OF THE STUDY ; 1. To compare and contrast the in-hospital outcomes of patients with Acute Myocardial infarction with normal Glucose Metabolism and Abnormal Glucose Metabolism – Impaired Glucose Tolerance. 2. To study the effect of Impaired Glucose Tolerance on the left ventricular function in these patients. 3. To assess the functional capacity of the patients with Myocardial infarction with Impaired Glucose Tolerance. CONCLUSION : Impaired Glucose Tolerance in patients with Acute ST elevation Myocardial Infarction is associated with ; increased incidence of arrhythmias, increased incidence of Congestive Heart Failure, increased incidence of recurrent angina, increased incidence of Left Ventricular Clot, increased incidence of in-hospital death. Impaired Glucose Tolerance is also associated with decrease in the left ventricular function as suggested by decrease in the ejection fraction in this group of patients and increase in the Wall Motion Score Index. Impaired Glucose Tolerance is associated with decrease in the functional capacity during the Pre discharge Treadmill Test.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Impaired Glucose Tolerance ; Acute ST Elevation ; Myocardial Infarction ; A Perspective study.
Subjects: MEDICAL > Cardiology
Depositing User: Kambaraman B
Date Deposited: 06 Jul 2017 04:39
Last Modified: 06 Jul 2017 10:18
URI: http://repository-tnmgrmu.ac.in/id/eprint/1076

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