A Clinical Study on the Effectiveness of Constitutional Treatment in the Prognosis of Pre-Diabetes based on Glycated Hemoglobin

Mahima, S (2019) A Clinical Study on the Effectiveness of Constitutional Treatment in the Prognosis of Pre-Diabetes based on Glycated Hemoglobin. Masters thesis, Sarada Krishna Homoeopathic Medical College, Kulasekharam.


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NEED FOR THE STUDY: Before people develop type 2 diabetes, they almost always have Pre-diabetes. Recent research has shown that some long term damage to the body, especially the heart and circulatory system, may already be occurring during Pre-diabetes. People with Prediabetes can prevent type-2 diabetes by eating healthy diet, being physically active, and managing their weight. So identifying people with Pre-diabetes is very much important. This study is planned to decrease the risk of type-2 Diabetes & heart disease by reducing blood sugar levels evidenced by HbA1C using Homoeopathic constitutional treatment. Homoeopathy can offer a safe, simple, low cost and effective treatment in preventing type-2 diabetes. The dominant school of medicine provides various pharmacotherapeutics as well as insulin therapy which brings down the blood sugar level, but the chances of developing other systemic disorders due to its prolonged usage is very much high. Prevention is always better than cure. So preventing diabetes by identifying and treating people with Pre-diabetes would always prove better than getting treatment after being diagnosed for diabetes. AIMS & OBJECTIVES: 1. To study the improvement of the patient based on HbA1c levels in patients with pre-diabetes. 2. To study the history and clinical presentations of individuals diagnosed with prediabetes. MATERIALS AND METHODS: STUDY SETTING: Thirty subjects diagnosed with pre-diabetes are selected from the Out Patient Departments or in the In Patient Departments and Peripheral Centres of Sarada Krishna Homoeopathic Medical College Hospital, Kulasekharam based on the inclusion criteria. STUDY DESIGN: An observational study with Homoeopathic intervention in pre-diabetes assessed by before and after treatment values of HbA1c. Study was conducted in patients who are matching with inclusion criteria after taking the case history, physical examination and investigations. SELECTION OF SAMPLES AND SAMPLE SIZE: Purposively selected 30 diagnosed cases of pre-diabetes (HbA1c 5.7%-6.4%) were taken for the study. SAMPLING TECHNIQUE: Purposive sampling technique was used in this study. METHODOLOGY: Purposive selection of 30 cases of pre-diabetes from the OPD, IPD and peripheral OPD centres of Sarada Krishna Homoeopathic Medical College Hospital, Kulasekharam. Pretest was done in the patients presenting with the symptoms of pre-diabetes and based on the patients physique & family history. The case details were recorded in standardized case recording format of Sarada Krishna Homoeopathic Medical College Hospital. Then the cases were analysed and totality was evaluated. Repertorisation was done if needed and a well selected remedy was prescribed based on totality. INCLUSION CRITERIA: • Adults in the age group of 20-55 years, both males and females. • Patients with the clinical presentation of pre-diabetes. • Persons with a hereditary tendancy to diabetes and with a possible physique. EXCLUSION CRITERIA: • People below the age of 20 years and above the age of 55 years. • Pregnant ladies. • Patients under other systems of treatment. • Patients suffering from other systemic diseases. CONCLUSION: This study, titled, “A CLINICAL STUDY ON THE EFFECTIVENESS OF CONSTITUTIONAL TREATMENT IN THE PROGNOSIS OF PRE-DIABETES BASED ON GLYCATED HEMOGLOBIN” was conducted in Sarada Krishna Homoeopathic Medical College & Hospital with a sample of 30 cases. HbA1c values before and after the treatment were analysed. The study result showed that maximum number of patients in the age group of 50-55 years were affected with pre-diabetes. Males are more affected than females. Of the affected females most of them were housewives. Out of 30 cases, about 28 patients had a family history of diabetes. Majority of the individuals belong to rural area. Most of the individuals in the study belonged to middle class socio economic status. BMI of 13 cases in the study were in the over weight category. Sulphur was the most indicated remedy followed by Lycopodium in second position. 200th potency was used in most of the cases. In this study of 30 cases, about 27 cases showed an improvement in HbA1c value, after the treatment the HbA1c value was below 5.7%. The statistical analysis for testing the significance of the study by ‘t’ test showed that Homoeopathic treatment had a role in reducing glycated hemoglobin in Pre-diabetes and thereby to check the progression of pre-diabetes to diabetes. SUMMARY: Present study includes a sample of 30 patients diagnosed to pre-diabetes and in each case HbA1c value were estimated for a period of every three months. Maximum number of persons with pre-diabetes fall under the age group of 50-55 years, about 13 cases; 9 persons come under the age group of 44-49, 3 come under the age group of 38-43 ; 3 people come in the age group 32-37 ; 2 come under the age group of 26-31 and none of them fall under the age group of 20-25 years. Study reveals that males are more affected than females. Of the affected females most of them were housewives, 4 were teachers ; 4 were businessmen ; 3 coolies; 2 drivers ; 2 religious persons ; 2 Govt. Employees and auditor, Army officer, Security Gaurd, Carpenter, Mechanical Engineer and Bank employee were 1 in number each. Out of 30 patients, about 28 of them had a family history of Diabetes mellitus, 1 with a family history of hypertension and 1 with no family history. Out of 30 cases,25 belong to rural area and 5 belong to urban area. In the study 50% of the individuals with pre-diabetes come under middle class, 40% are high class individuals and the remaining 10% come under low socio economic status. About 13 patients (43.33%) were found to be over weight, 12 patients (40%) were obese, 2 patients (6.67%) were severely obese and 3 patients (10%) were of normal weight. As shown in the studies, it is evident that SULPHUR ranges the highest position(9 patients),followed by LYCOPODIUM (4 patients), then CALCAREA CARB, FLOURIC ACID, NUX VOMICA, PULSATILLA, PHOSPHORUS AND LACHESIS came in the next postion (2 patients each); NATRUM MURIATICUM , ACID PHOSPHORICUM, STAPHYSAGRIA, NITRIC ACID and ARSENICUM ALBUM in the last position. (1 patient each). Out of 30 cases 15 patients were given with 200th potency, 7 patients were given with 30th potency, 5 were given with 0/3 potency and 3 patients were given 0/1 potency.27 cases showed an improvement with a reduction in HbA1c value, below 5.7%, after the administration of our medicine.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Constitutional Treatment ; Prognosis of Pre-Diabetes ; Glycated Hemoglobin ; Clinical Study.
Subjects: AYUSH > Practice of Medicine
Depositing User: Subramani R
Date Deposited: 05 Aug 2019 01:03
Last Modified: 27 Mar 2020 15:13
URI: http://repository-tnmgrmu.ac.in/id/eprint/10736

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