Ezhilarasan, B (2018) Pharmacognostical, Phytochemical including Isolation of Cryptolepine and In Vitro Antioxidant, Alpha - Amylase Effect, Antimycobacterial and In Vivo Antihistaminic Activities of Sida acuta Burm. (Leaves). Masters thesis, College of Pharmacy, Madurai Medical College, Madurai.
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Abstract
The present investigations draws the following conclusion (succeeding) inference. • Pharmacognostical parameters for the leaves of Sida acuta were evaluated with additional scintfic data for the previous work, Multicellular trichomes and anamocytic stomata are affixed information to this plant. • Quantitative estimation helps to identify the tannic acid, gallic acid and flavonoids equivalents present in the hydro-alcoholic extract of Sida acuta. • TLC studies recorded the presence of coumarins, flavonoids,cryptolepine. • The phytochemical screening of the hydro-alcoholic extract (70%) Sida acuta (Leaf) powder revealed the presence of alkaloids, carbohydrates, cardiac glycosides, coumarine glycosides, sterols, saponins, tannins, phenolic compounds, flavonoids, proteins, amino acids, terpenoids, fixed oils, gum, mucilage, quinone, coumarine, resins.The aqueous extract of Sida acuta (Leaf) revealed the presence of alkaloids, carbohydrates, cardiac glycosides, coumarine glycosides, sterols, saponins, tannins, phenolic compounds, flavonoids, proteins, amino acids, terpenoids, fixed oils, gum, mucilage, quinone, coumarine, resins, pholotannins. • Isolation of indoloquinoline alkaloids such as cryptolepine. • Spectral studies carried out such as UV, IR, H1 NMR 13C NMR and Mass spectroscopy. • Pharmacological screening potentiates the biological invitro antioxidant, invitro alpha amylase inhibitory effect, invitro anti micobacterial effect, invivo antihistaminic effect. • Further investigation may be carried out for the bio-active fraction for its potential pharmacological effects. • Future research studies may be extended to isolate other phyto-constituents present in this plant.
| Item Type: | Thesis (Masters) |
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| Additional Information: | Reg.No.261620701 |
| Uncontrolled Keywords: | Pharmacognostical ; Phytochemical ; Isolation of Cryptolepine ; In Vitro Antioxidant ; Alpha - Amylase Effect ; Antimycobacterial Activities ; In Vivo Antihistaminic Activities ; Sida acuta Burm. |
| Subjects: | PHARMACY > Pharmacognosy |
| Depositing User: | Subramani R |
| Date Deposited: | 28 Jun 2019 15:50 |
| Last Modified: | 28 Jun 2019 15:50 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/10650 |
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