Preparation and Evaluation of Momordica Charantia Nanophytosomes and Efficacy on MDA-MB Human Breast Cancer

Sivakami, G (2018) Preparation and Evaluation of Momordica Charantia Nanophytosomes and Efficacy on MDA-MB Human Breast Cancer. Masters thesis, Arulmigu Kalasalingam College of Pharmacy, Krishnankoil.

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Abstract

Nanophytosomes of aqueous extract of momordica charantia was successfully prepared and tested for breast cancer cell lines. The aqueous extract was evaluated phyto chemical screening followed by all characterization studies. Phytochemical screening study remaining that the extract consists of flavanoids. The characterization study showed that the phytosomes are having nano size, good stability properties with round to spherical shape with smooth surfaces. The MTT assay, extract and nanophytosomes showed that nanophytosomes are having more anti cancer activity. When compared with aqueous extract against MDA-MBbreast cancer cell lines. Hence, the prepared nanophytosomes showed excellent in vitro anti cancer activity. This work can be further extended to clinical trials.

Item Type: Thesis (Masters)
Additional Information: Reg.No: 261610403
Uncontrolled Keywords: Momordica Charantia Nanophytosomes ; MDA-MB Human Breast Cancer ; Preparation ; Evaluation.
Subjects: PHARMACY > Pharmaceutics
Depositing User: Subramani R
Date Deposited: 25 Jun 2019 03:44
Last Modified: 25 Jun 2019 03:44
URI: http://repository-tnmgrmu.ac.in/id/eprint/10611

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