Sidharthan, K (2014) Effect of Reperfusion on right ventricular function in acute anterior wall ST elevation myocardial function. Masters thesis, Madras Medical College, Chennai.
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Abstract
INTRODUCTION : Coronary artery disease is one of the leading cause of morbidity and mortality in the world. In 19th century coronary artery disease is more prevalent in the developed countries. Now it is becoming epidemic in developing countries also. There is a five times increased prevalence of coronary artery disease in 1986 when compared to 1976. When compared to other countries in the world, SAARC countries have more prevalence of cardiovascular diseases. According to the Global burden of Disease Study this region will have more cardiovascular disease than the rest of the world by 2020. The main reasons for the increased incidence of coronary artery disease in this part of the world are diabetes mellitus, hypertension, smoking, stress, obesity, sedentary life style susceptible genetics and unhealthy diet. The spectrum of coronary artery disease is from acute coronary syndrome to stable angina. Acute coronary syndrome is the most important cause for morbidity and mortality among coronary artery disease. Acute myocardial infarction is usually due to anterior or inferior wall infarction. AIMS AND OBJECTIVES : 1. To study the effect of reperfusion therapy on right ventricular function in patients with acute anterior wall ST elevation myocardial infarction. 2. To study the utility of echocardiographic parameters like tricuspid annular plane systolic excursion, tricuspid annular peak systolic velocity, right ventricular myocardial performance index in the evaluation of right ventricular function in patients with acute anterior wall ST elevation myocardial infarction. CONCLUSION : This study has showed that right ventricular dysfunction may also occur in patients with acute anterior wall ST elevation myocardial infarction patients. Right ventricular dysfunction is explained by many factors, namely the role of left ventricular dysfunction causing right ventricular dysfunction, ventricular interdependence which was mediated mainly through the inter ventricular septum, common myocardial fibers shared by both the right ventricle and the left ventricle and the blood supply of the anterior wall of right ventricle by the left anterior descending coronary artery. Even though both tricuspid annulus planar systolic expansion and Tei index are more sensitive to recognize right ventricular dysfunction, tricuspid annulus planar systolic expansion is a simple, easy and rapid method to measure the right ventricular function. It is important to recognize right ventricular dysfunction early because right ventricular dysfunction may cause cardiogenic shock and hence treating right ventricular dysfunction may reduce morbidity and mortality.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | reperfusion ; right ventricular function ; acute anterior wall ST Elevation ; myocardial function. |
| Subjects: | MEDICAL > Cardiology |
| Depositing User: | Kambaraman B |
| Date Deposited: | 06 Jul 2017 00:41 |
| Last Modified: | 06 Jul 2017 09:56 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/1054 |
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