Jeevitha Rajalakshmi, K (2016) Study of Carotid Intima Media Thickness as a Predictor of Macrovascular Complications in Type 2 Diabetes Mellitus. Masters thesis, Kilpauk Medical College, Chennai.
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Abstract
BACKGROUND: The global burden due to diabetes is mostly contributed by type 2 diabetes which constitutes 80% to 95% of the total diabetic population. Diabetes mellitus is the most common metabolic disease which is prevalent in every part of the world and is a major public health challenge of the twenty-first century. The most common cause of mortality in patients with type 2 diabetes mellitus (T2DM) are cardiovascular diseases. Carotid artery intima-media thickness by B mode ultrasound is a simple, non-invasive and reproducible imaging parameter to evaluate atherosclerotic vascular diseases. AIM OF THE STUDY: 1. To compare the carotid intima media thickness in case group and in control population. 2. To find the association of increased carotid intima media thickness and CAHD/CVA/PVD. 3. To assess the usage of carotid intima media thickness as a early predictor of macrovascular complications in type 2 Diabetics. METHODS: This is a Case control Study conducted during February 2015 to July 2015. 50 type 2 diabetes mellitus patients with macro vascular complications as cases and 50 type 2 diabetes mellitus patients without macro vascular complications as control group. Ultra sonographic scanning of the carotid arteries is performed by using a high resolution B mode ultrasound colour Doppler imaging and Carotid intima media thickness is measured in cases and controls. RESULTS: The present study showed increased values of CIMT in Diabetic patients with macro vascular complication than Diabetic patients without macro vascular complications and it was statistically significant. CONCLUSION: Thus, measurement of carotid intima media thickness by ultrasound Doppler is reliable and helps in early medical intervention to take care of risk factors and life style modification and may reduce incidence of macro vascular complications of type 2 diabetes mellitus.
| Item Type: | Thesis (Masters) |
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| Additional Information: | Reg.No.201311154 |
| Uncontrolled Keywords: | Carotid intima media thickness ; type 2 diabetes mellitus ; macro vascular complications ; coronary artery disease ; peripheral vascular disease ; cerebrovascular accident. |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 06 Feb 2019 05:22 |
| Last Modified: | 06 Feb 2019 05:22 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/10513 |
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