A Study of Clinical and Etiological Profile of Focal Seizures

Revathy, V (2016) A Study of Clinical and Etiological Profile of Focal Seizures. Masters thesis, Thanjavur Medical College, Thanjavur.


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BACKGROUND: The etiology of seizures is directly linked to the type of seizure. In focal seizures, localisation of abnormalities ranges from 28 to 80%. as observed in various studies. A proper history along with necessary investigations is very much essential in identifying the etiology of seizures. Since focal seizures are mostly associated with focal structural lesions, it is imperative to identify the correct etiology and to institute proper treatment. Hence we take up this study to evaluate the clinical and etiological profile of new onset focal seizures. AIMS AND OBJECTIVES: To study the clinical profile and to evaluate the etiology of new onset focal seizures. METHODS: The study group includes patients with new onset focal seizures age > 12 years who presented to the Neurology and Medicine outpatient departments in Thanjavur Medical College Hospital, Thanjavur. Those who complied with the inclusion and exclusion criteria were subjected to detailed history taking and neurological examination and necessary blood and imaging investigations were done to find out the etiology and analysis was performed with appropriate statistical methods. RESULTS: In the study conducted in 50 patients with new onset focal seizures, majority of the patients belonged to the age group 21-30 years. Focal seizures with secondary genreralization was the most common type followed by focal seizures without dyscognitive features and focal seizures with dyscognitve features. In younger age group less than 30 years, neuroinfections were the most common cause. In age more than 50 years, metabolic causes and cerebrovascular diseases predominate. CONCLUSIONS: The spectrum of etiology for focal seizures varies which include old cerebrovascular diseases, neuroinfections, metabolic causes, tumors, and idiopathic. Hence, in all cases of new onset focal seizures, complete evaluation is required to identify the etiology and hence to initiate proper treatment, thereby the morbidity and mortality in the community can be reduced.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Focal seizures ; Focal seizures with and without dyscognitive features ; Focal seizures with secondary generalization.
Subjects: MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 06 Feb 2019 02:46
Last Modified: 06 Feb 2019 02:46
URI: http://repository-tnmgrmu.ac.in/id/eprint/10501

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