C-Reactive Protein and Glycemic Control in Adult with Type 2 Diabetes Mellitus

Nanubala, Siva Krishna (2016) C-Reactive Protein and Glycemic Control in Adult with Type 2 Diabetes Mellitus. Masters thesis, PSG Institute of Medical Sciences & Research, Coimbatore.

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Abstract

INTRODUCTION: In worldwide, type 2 diabetes prevalence is increasing in the all age group population. This is a major cause for death and various non fatal complications. In a recent study it is proved that high risk patients with type 2 diabetes mellitus can be reduced by modification of life styles AIMS AND OBJECTIVES: 1. Correlation of glycaemic control as estimated by Hba1c with C-Reactive protein in type-2 diabetic patients. 2. To determine if better control of Hba1c reduces CRP levels. MATERIAL AND METHODS: We recruited 30 study patients who presented with poor glycemic control and we measured hba1c and hscrp levels and the results were statistically analysed. RESULTS: Hba1c at baseline, in the study population of 30, 36.7% of people are having hba1c of >11 % and 16.7% of people are having hba1c between 8-9. HbA1C after 6 months, in the study population of 30, 84 % of people are having HbA1c between 8-9 and 8% of people are having 9-10 and >11 % respectively. HsCRP at baseline, in the study population of 30,at baseline 63% of people are having hsCRP of <5% and 6.7 % of people are having >25. HsCRP after 6 months, in the study population 48% of people are having hsCRP of <5 and 8% of people are between 15-25 CONCLUSION: Hba1c at baseline, minimum value is 8 and maximum is 15.2. Hba1c after 6 months, minimum value is 6 and maximum is 8.3. So in this study when hba1c is compared with baseline hba1c, patient has got good glycemic control, but stastically not significant [p>0.05]. HSCRP at baseline, minimum value is 10 and maximum is 32. Hba1c after 6 months, minimum value is 2 and maximum is 20.4. So in this study when HSCRP is compared with baseline HSCRP, shows stastically significant [p<0.05]

Item Type: Thesis (Masters)
Additional Information: Reg.No.201311505
Uncontrolled Keywords: High sensitive C reactive protein (HsCRP) ; Glycoslated hemoglobin (HbA1C) ; Glycemic Control ; Adult ; Type 2 Diabetes Mellitus.
Subjects: MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 05 Feb 2019 23:45
Last Modified: 05 Feb 2019 23:45
URI: http://repository-tnmgrmu.ac.in/id/eprint/10481

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