Kannan, R (2014) Stratification of Coronary Artery Morphology in Diabetic patients with Microalbuminuria. Masters thesis, Madras Medical College, Chennai.
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Abstract
INTRODUCTION : Ancient texts in India mention about the disease “Madhumeha” which corresponds to the term “Diabetes mellitus”. It suggests that diabetes should have been in India even before 2500 BC. But no evidence is available to know its prevalence. Diabetes Mellitus is a chronic metabolic disease present throughout the world that leads to increased morbidity and mortality which is major worry for the public health care workers. Inspite of vast developments in the treatment of Diabetes mellitus there is an increased prevalence and complications of this disease. In 2011 366 million people with diabetes were present throughout the world and it is expected to increase to 552 million in 2030. Most of them live in low- and middle-income countries like India. These countries are going to have the greatest increase over the next 19 years. The ICMR-INDIAB national studypublished that there are 62.4 million people with type 2 diabetes and 77 million people with pre-diabetes in India. Thesenumbers are expected to increase to 101 million by the year 2030.There are few population based studies on complications of diabetes in India.(63,64) According to those studies the prevalence of diabetic retinopathy was 17.6%, microalbuminuria was 26.9% neuropathy was 26.1%, coronary disease was 21.4% and peripheral artery disease was 6.3%. A study have shown that microalbuminuria was related to coronary artery disease , dyslipidemia, and hypertension. This indicates that microalbuminuria enhances the risk of coronary artery disease along with other risk factors. Microalbuminuria suggests not only the pressure effect onrenal vessels but significant atherosclerotic disorder in the wholevascular system. Hence microalbuminuria may a marker for the underlying vascular disorder and not alone suggesting a renal disorder. AIM AND OBJECTIVES : To stratify the coronary angiographic characteristics in Type2 Diabetes Mellitus patients with Microalbuminuria suspected of having Ischemic Heart Disease. CONCLUSION : The following conclusions are made from this study. 1. IN Type 2 Diabetes mellitus presence of micoalbuminuria predicts a severe form of coronary disease with complex and severe coronary lesions. 2. Elderly with Type2 Diabetes Mellitus with microalbuminuria have severe form of coronary disease. 3. There were increased males having microalbuminuria than females. 4. The smokers with diabetes had an increased severity of coronary Artery disease and especially in the patients with microalbuminuria. 5. People with microalbuminuria had significant diffuse disease with thin vessels unsuitable for revascularisation.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Stratification ; Coronary Artery Morphology ; Diabetic patients ; Microalbuminuria. |
| Subjects: | MEDICAL > Cardiology |
| Depositing User: | Kambaraman B |
| Date Deposited: | 05 Jul 2017 23:47 |
| Last Modified: | 06 Jul 2017 09:44 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/1047 |
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