A Clinical Study on Visual Outcome following Uveitis

Mythili, T (2016) A Clinical Study on Visual Outcome following Uveitis. Masters thesis, Thanjavur Medical College, Thanjavur.

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Abstract

INTRODUCTION: Uveitis is one of the most common forms of intraocular inflammation. It includes a large group of inflammatory diseases of diverse etiology. The variation in the spectrum of the disease is due to complex geographic, ecological, racial and socio economic differences ( 2 ).It causes vision loss either directly or via complications such as cataract, glaucoma, macular edema and others. Anterior uveitis is common of all types of uveitis (57.4%) with an incidence of 17 cases per 100,000 population. Acute anterior uveitis cause painful red eye with mild vision loss (12) but still contributes significantly to overall burden. The precise cause of anterior uveitis is obscure and correct diagnosis and management is quite challenging. The morbidity associated is moderately high. Acute, unilateral, non infectious and non-granulomatous forms of anterior uveitis occur more frequently. Idiopathic anterior uveitis is common in all age groups. Mean age of presentation is 38 yrs. It is common in males (61.2%) compared to females (38.6%). Herpetic anterior uveitis accounts (16.7%), lens induced uveitis (14.6%) and leprosy uveitis (4.9%) are common in elderly. Fuch’s heterochromic uveitis (9.8%), uveitis associated with spondyloarthropathy (8.2%) and traumatic uveitis (7.8%) are common in middle aged. AIMS AND OBJECTIVES: 1. To evaluate the etiology, clinical features, systemic associations and severity of uveitis. 2. To analyse the visual outcome following uveitis. MATERIALS AND METHODS: This is a prospective study which includes 80 patients with anterior uveitis of various etiologies presented to our department at Thanjavur medical college from July 2014 – September 2015.They were subjected to detailed clinical examination and relevant investigations. A proforma was drawn up and following details were recorded for each patient :age and sex, history related to trauma, surgery and specific systemic associations of uveitis, clinical examination of signs and symptoms of uveitis including general systemic examination. They were reviewed according to the severity of uveitis and followed up for a period of 15 months. According to improvement/worsening of the disease activity they were managed. OBSERVATION AND RESULTS: The ratio of uveitis in male to female is 1.6:1 with 96.25% bilateral and 3.75% unilateral presentation. With regard to etiology 17.5% had idiopathic 8.75% infective, 47.50% traumatic, 5% lens induced and 21.25% post operative uveitis. Vision loss accounted 7.50% due to cataract, 6.25% macular edema and 10% due to glaucoma. Visual outcome improved in 91.50% of the patients. Blindness due to anterior uveitis is 1.25%. CONCLUSION: To conclude the study, uveitis threatens to become the major cause of ocular morbidity but patients gets good final visual outcome with detailed clinical examination and initiation of proper management. Cases presented earlier even with severe uveitis had favorable response to treatment and good prognosis in visual outcome than those presented late with uveitic sequalae and with co-morbid risk factors irrespective of etiology.

Item Type: Thesis (Masters)
Uncontrolled Keywords: anterior uveitis ; visual outcome ; Idiopathic ; traumatic uveitis.
Subjects: MEDICAL > Ophthalmology
Depositing User: Devi S
Date Deposited: 29 Jan 2019 18:34
Last Modified: 29 Jan 2019 19:33
URI: http://repository-tnmgrmu.ac.in/id/eprint/10430

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