A Clinical Assessment and Evaluation of Mantha Sanni (Autism Spectrum Disorder) with Siddha therapeutic management in children

Dharshini Priya, G (2018) A Clinical Assessment and Evaluation of Mantha Sanni (Autism Spectrum Disorder) with Siddha therapeutic management in children. Masters thesis, National Institute of Siddha, Chennai.


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A child who has been determined to require special attention is called as Special children. Children with multiple disabilities associated with impairment in social, cognitive skills, communication skills, behavioural changes and sensory issues called Autism spectrum disorder. Many Allopatyhic medications like respiridon, valporic acid are widely used for ASD. Not all the patients benefit from this treatment. However this drug has to shown undesirable side effects. It is in the text that we have undertaken a review of the Siddha formulation which could help management of ASD. In the view of the above, great efforts have been made to find out the Siddha medicine and methologies to improve the life styles of ASD children. The available literature on Manthasanni reveals that this is a disease of Autism spectrum disorder. For the purpose of study about Mantha sanni, 30 patients of both sexes were selected between the age group of 3-12 years. The study revealed that the incidence of the disease is greater in the age group of 3-6 years. The study revealed that.43% of the cases belonged to high socio economic status. Regarding unknown aetiology 100% of the cases developed diseases after the age of one and half years. In Uyir thathukkal vatham, pitham, kabam were affected in 100% of cases. In Udal thathukkal Saram was affected in 2.6% cases. In Envagai thervugal, Neikuri indicated kabaneer (Pearl like shape) in all the cases. Patients attending the kuzhandhai maruthuvam OPD of Ayothidoss Pandithar Hospital, NIS having the complaints of Mantha sanni is diagnosed and taken for this study. Clinical diagnosis of Mantha sanni is done on the basis of clinical feature described in Balavagadam text. Autism is an umbrella term for Autism spectrum disorder which is charscterised by Constant problem with social communication and interactions across a variety of contexts Early onset of symptoms (typically in the first two years of life). Repetitive, restricted patterns of behaviour, Activities and interests. Symptoms that cause major impairment in social, educational and other important area of functioning. It is called a spectrum because of the wide range of symptoms and impairment level in children can have. Some are only mildly affected by their symptoms, while the other children are severely disabled. Diagnosis has been made based on the specially prepared proforma, which includes all clinical signs and symptoms of the disease. A detailed history has been taken and recorded. Clinical studies were carried out after obtaining proper permission from IEC of National Institute of Siddha via IEC number NIS/IEC/2016/11-19/ 14.10.2016 and the trial was registered in Clinical trial registry of India via CTRI number CTRI/2017/05/008698. The authentications of the new drugs are obtained from the Medicinal Botanist of NIS and the medicine is prepared in the Gunapadam laboratory of NIS under the guidance and superviser of the guide. Physicochemical and Biochemical analysis for the drug has been carried out. In treatment aspect all the 30 cases were treated with Kuruver kudineer internally and Sambrani and mysatchi pugai (externally) for an average of 90 days.The observation made during this study showed that the trial medicine was clinically effective. After the treatment period of 3 months, the Summary of case study were shown in all the 30 ASD children are improved cognitive functions, eye to eye contact and reduced hyperactivity behaviour. There was sitting tolerance, enhanced the mind calming activity. Able to mingle the other children and try to speak the verbal with limited skills and having good sound sleep. So the Siddha internal and external therapies are enhancing the quality of life of ASD children. The potency of drug was studied by pharmacological, phytochemical, physicochemical and biochemical analysis. It showed that the drug has good action. The drug also has Anxiolytic activity. All the patients showed very good response. No patients developed any adverse effects. The action of trial drug and progress in the patients was encouraging. CONCLUSION: In this study, results were found to be improvement in all the cases. No adverse effects were noticed during the treatment. Further follow up of these patients showed good recovery and fine improvement. The preparation of the medicine is simple as well as economical. The trial drug has anxyiolytic actions. So it is concluded that for the disease Mantha sanni, the treatment with Kuruver kudineer is good, in the view of efficacy and safety. The Global burden of Mantha sanni (Autism spectrum disorder), increasing prevalence and its impact in reducing the quality of life in children has prompted the author to choose an efficient and nutritive drug which is believed to good in central nervous system. The treatment of Mantha sanni with Kuruver Kudineer has showed good response with no adverse effect, very effective and simple to administer. This has, in turn, provided a golden opportunity for new drug established in the management of Mantha sanni. Our perception of autism has evolved over time. Sixty years ago autism was nothing more than an unrecognized developmental delay generally lumped in with mental retardation. Today it is recognized as an independent neurologically based disorder of significance, a major public health problem, and a topic of much research. So we will overcome this disease by regular practice of Siddha treatment and also with help of Role of Families, Educational services, Effective Interventions, Public Policies, Personal preparation. Further study is recommended for scientific validation to prove its clinical efficacy in multicenter clinical study.

Item Type: Thesis (Masters)
Additional Information: (Reg.No.321514203)
Uncontrolled Keywords: Clinical Assessment and Evaluation ; Mantha Sanni ; Autism Spectrum Disorder ; Siddha Therapeutic Management ; Children.
Subjects: AYUSH > Kuzhanthai Maruthuvam
Depositing User: Subramani R
Date Deposited: 29 Dec 2018 11:06
Last Modified: 29 Dec 2018 11:06
URI: http://repository-tnmgrmu.ac.in/id/eprint/10264

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